2-Indanone oxime

Base Information

• Chemical Name: 2-Indanone oxime
• CAS No.: 3349-63-1
• Molecular Formula: C9H9NO
• Molecular Weight: 147.177
• Hs Code.: 2928000090
• European Community (EC) Number: 222-105-2
• NSC Number: 62556,54456
• UNII: 9OUM5TX75K
• DSSTox Substance ID: DTXSID4062987
• Nikkaji Number: J138.290J
• Wikidata: Q27115971
• Mol file: 3349-63-1.mol

Synonyms:2-Indanone oxime;3349-63-1;2-Indanone, oxime;N-(1,3-dihydroinden-2-ylidene)hydroxylamine;2H-Inden-2-one, 1,3-dihydro-, oxime;1,3-Dihydro-2H-inden-2-one oxime;UNII-9OUM5TX75K;9OUM5TX75K;1H-inden-2(3H)-one oxime;EINECS 222-105-2;NSC 54456;NSC 62556;NSC-54456;NSC-62556;2-Indanoneoxime;2H-Inden-2-one,3-dihydro-, oxime;indan-2-one oxime;2-Indanone oxime, 96%;NCIOpen2_000087;1,3-dihydroinden-2-one oxime;SCHEMBL5190200;DTXSID4062987;CHEBI:34291;NSC54456;NSC62556;AKOS000278373;1,3-Dihydro-2H-inden-2-one oxime #;WS-01448;CS-0323498;FT-0634793;D86143;A821798;J-019213;Q27115971

Chemical Property of 2-Indanone oxime

Chemical Property:

• Appearance/Colour: white powder
• Vapor Pressure: 0.000383mmHg at 25°C
• Melting Point: 152-154 °C(lit.)
• Refractive Index: 1.617
• Boiling Point: 304.453 °C at 760 mmHg
• Flash Point: 183.591 °C
• PSA: 32.59000
• Density: 1.2 g/cm³
• LogP: 1.61540
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 147.068413911
• Heavy Atom Count: 11
• Complexity: 160

Purity/Quality:

98%min ^*data from raw suppliers

2-Indanone oxime 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1C(=NO)CC2=CC=CC=C21
• Uses: 2-Indanone oxime may be used for the preparation of 2-aminoindane hydrochloride by using active palladium catalyst.

Technology Process of 2-Indanone oxime

There total 5 articles about 2-Indanone oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methoxy-2,3-dihydro-1H-inden-1-ol (103324-09-0) → indan-2-one oxime (3349-63-1)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous H₂SO₄

With sulfuric acid;

DOI:10.1021/jo01186a010

Reference yield:

trans-2-bromo-1-indanol (10368-44-2,78684-69-2) → indan-2-one oxime (3349-63-1)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium methylate; methanol

2: aqueous H₂SO₄

With methanol; sulfuric acid; sodium methylate;

DOI:10.1021/jo01186a010

Reference yield:

2-indanone (615-13-4) → indan-2-one oxime (3349-63-1)

Guidance literature:

DOI:10.1021/jo01186a010

upstream raw materials:

2-indanone

hydroxylamine

2-methoxy-2,3-dihydro-1H-inden-1-ol

trans-2-bromo-1-indanol

Downstream raw materials:

2,3-dihydro-1H-inden-2-amine

2-aminoindane hydrochloride

2-(phenylsulfonyl)-1',3'-dihydrospiro[1,3,2-dithiaphosphetane-4,2'-indene]2-sulfide

Trithio-indan-2-on

Refernces

• 1、 -. "SUBSTITUTED CYCLIC COMPOUNDS AND METHODS OF USE". Paragraph 0191; 0196. . Retrieved 2014/06/24.