2-Acetamido-3-nitro-9-fluorenone

Base Information

• Chemical Name: 2-Acetamido-3-nitro-9-fluorenone
• CAS No.: 13287-73-5
• Molecular Formula: C₁₅H₁₀N₂O₄
• Molecular Weight: 282.255
• Hs Code.: 2924299090
• NSC Number: 60826
• DSSTox Substance ID: DTXSID40157825
• Nikkaji Number: J74.909E
• Wikidata: Q83025986
• ChEMBL ID: CHEMBL508088
• Mol file: 13287-73-5.mol

Synonyms:2-acetamido-3-nitro-9-fluorenone

Chemical Property of 2-Acetamido-3-nitro-9-fluorenone

Chemical Property:

• Vapor Pressure: 5.14E-14mmHg at 25°C
• Boiling Point: 592.6°Cat760mmHg
• Flash Point: 312.2°C
• PSA: 91.99000
• Density: 1.487g/cm³
• LogP: 3.36080
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 282.06405680
• Heavy Atom Count: 21
• Complexity: 473

Purity/Quality:

99% ^*data from raw suppliers

2-ACETAMIDO-3-NITRO-9-FLUORENONE AldrichCPR ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1=C(C=C2C3=CC=CC=C3C(=O)C2=C1)[N+](=O)[O-]

Technology Process of 2-Acetamido-3-nitro-9-fluorenone

There total 9 articles about 2-Acetamido-3-nitro-9-fluorenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-acetylamino-9-fluorenone (3096-50-2) → N-2-(3-Nitro-9-oxo-fluorenyl)-acetamid (13287-73-5)

Guidance literature:

With nitric acid;

Reference yield:

2-nitro-9H-fluoren-9-one (3096-52-4) → N-2-(3-Nitro-9-oxo-fluorenyl)-acetamid (13287-73-5)

Guidance literature:

Multi-step reaction with 5 steps

1: sodium sulfide; diluted NaOH-solution; alcohol

2: pyridine

3: glacial acetic acid; nitric acid

4: concentrated sulfuric acid

With pyridine; sodium sulfide; sodium hydroxide; ethanol; sulfuric acid; nitric acid; acetic acid;

Reference yield:

2-amino-9-fluorenone (3096-57-9) → N-2-(3-Nitro-9-oxo-fluorenyl)-acetamid (13287-73-5)

Guidance literature:

Multi-step reaction with 4 steps

1: pyridine

2: glacial acetic acid; nitric acid

3: concentrated sulfuric acid

With pyridine; sulfuric acid; nitric acid; acetic acid;

upstream raw materials:

3-nitro-2-acetamidofluorene

2-acetylamino-9-fluorenone

2-amino-3-nitro-fluoren-9-one

acetic anhydride

Downstream raw materials:

N-2-(7-Chlor-3-nitro-9-oxo-fluorenyl)-acetamid