Hydroxylamine-O-sulfonic acid, N-acetyl-N-(4-chlorophenyl)-, compd. with pyridine (1:1)

Base Information

• Chemical Name: Hydroxylamine-O-sulfonic acid, N-acetyl-N-(4-chlorophenyl)-, compd. with pyridine (1:1)
• CAS No.: 91631-54-8
• Molecular Formula: C8H8ClNO5S.C5H5N
• Molecular Weight: 344.776
• Mol file: 91631-54-8.mol

Synonyms:

Chemical Property of Hydroxylamine-O-sulfonic acid, N-acetyl-N-(4-chlorophenyl)-, compd. with pyridine (1:1)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Hydroxylamine-O-sulfonic acid, N-acetyl-N-(4-chlorophenyl)-, compd. with pyridine (1:1)

There total 2 articles about Hydroxylamine-O-sulfonic acid, N-acetyl-N-(4-chlorophenyl)-, compd. with pyridine (1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(4-chlorophenyl)hydroxylamine (823-86-9) → N-sulfonoxy-p-chloroacetanilide pyridinium salt (91631-54-8)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether

2: sulfur trioxide / pyridine; CH₂Cl₂ / 120 h / Ambient temperature

With sulfur trioxide; In pyridine; diethyl ether; dichloromethane;

DOI:10.1021/ja00331a036

Reference yield:

pyridine (110-86-1) + N-(4-chlorophenyl)-N-hydroxyacetamide (1503-91-9) → N-sulfonoxy-p-chloroacetanilide pyridinium salt (91631-54-8)

Guidance literature:

With sulfur trioxide; In pyridine; dichloromethane; for 120h; Yield given; Ambient temperature;

DOI:10.1021/ja00331a036

Reference yield: 83.0%

N-sulfonoxy-p-chloroacetanilide pyridinium salt (91631-54-8) → ethyl sulfate (540-82-9) + N-(4-chlorophenyl)-N-hydroxyacetamide (1503-91-9)

Guidance literature:

In ethanol; at 40 ℃;

DOI:10.1021/ja00331a036

upstream raw materials:

pyridine

N-(4-chlorophenyl)-N-hydroxyacetamide

N-(4-chlorophenyl)hydroxylamine

Downstream raw materials:

ethyl sulfate

N-(4-chlorophenyl)-N-hydroxyacetamide

N-(2,4-dichlorophenyl)acetamide

4-acetaminophenol

Refernces