BIOPOL

Base Information

• Chemical Name: BIOPOL
• CAS No.: 29435-48-1
• Molecular Formula: C₄H₈O₃
• Molecular Weight: 104.106
• Mol file: 29435-48-1.mol

Synonyms:Butanoicacid, 3-hydroxy-, (R)-, homopolymer; Butyric acid, 3-hydroxy-, D-(-)-,polyesters (8CI); (R)-3-Hydroxybutyric acid homopolymer;Poly((R)-(-)-3-hydroxybutyrate); Poly(D-(3-Hydroxybutyrate));Poly(D-3-hydroxybutyric acid); Poly(D-b-hydroxybutyrate); Poly[(-)-3-hydroxybutyric acid];Poly[(R)-3-hydroxybutyrate]; Poly[D(-)-3-hydroxybutyric acid]; Poly[D(-)-b-hydroxybutyric acid]

Chemical Property of BIOPOL

Chemical Property:

• Melting Point: 175 °C
• PSA: 60.36000
• LogP: -1.49280
• Storage Temp.: -20°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

PHB ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Poly[(R)-3-hydroxybutyric acid (PHB) is a biodegradable and biocompatible polymer produced by several bacterial species, owing to its low resorbability and tunable properties, it may find uses in a variety of applications such as tissue engineering, controlled release systems etc.

Technology Process of BIOPOL

There total 189 articles about BIOPOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

(S)-(-)-β-methyl-β-propiolactone (65058-82-4) → (S)-3-Hydroxybutanoic Acid (6168-83-8,26063-00-3,29435-48-1)

Guidance literature:

With sodium hydroxide; In water; at 0 ℃; for 0.333333h;

DOI:10.1002/hlca.19870700513

Reference yield: 53.0%

(S)-3-hydroxybutyric acid methyl ester (53562-86-0) → (S)-3-Hydroxybutanoic Acid (6168-83-8,26063-00-3,29435-48-1)

Guidance literature:

With sodium hydroxide; In water; for 36h;

DOI:10.1002/(SICI)1522-2675(19981216)81:12<2430::AID-HLCA2430>3.0.CO;2-W

Reference yield: 47.0%

(S)-(-)-β-methyl-β-propiolactone (65058-82-4) → (S)-3-Hydroxybutanoic Acid (6168-83-8,26063-00-3,29435-48-1) + (R)-3-Mercaptobuttersaeure (115395-16-9)

Guidance literature:

With sodium hydrogensulfide; In water; Yields of byproduct given; 0 deg C, 1 h, then room temp., 24 h;

DOI:10.1002/hlca.19870700514

upstream raw materials:

pyridine

diethyl ether

malonic acid

acetaldehyde

Downstream raw materials:

2-isopropyl-5-methylcyclohexyl 3-hydroxybutyrate

acetaldehyde

acetone

3(R)-(4-Carboxy-2-nitrophenoxy)butyric acid

Refernces

• 1、 -. "PANTETHEINE DERIVATIVES AND USES THEREOF". Paragraph 2121. . Retrieved 2020/06/19.
• 2、 Coady, Tracey M.,Coffey, Lee,Kinsella, Michael,Lennon, Claire M.,Mareya, Tatenda M.,O'Reilly, Catherine. "Process Optimisation Studies and Aminonitrile Substrate Evaluation of Rhodococcus erythropolis SET1, A Nitrile Hydrolyzing Bacterium". . p. 512 - 520. Retrieved 2020/10/02.