4-tert-Butylpiperidine

Base Information

• Chemical Name: 4-tert-Butylpiperidine
• CAS No.: 1882-42-4
• Molecular Formula: C9H19N
• Molecular Weight: 141.257
• Hs Code.: 2933399090
• European Community (EC) Number: 217-539-4
• UNII: 7DZ9SC8WCC
• DSSTox Substance ID: DTXSID7062035
• Nikkaji Number: J199.702E
• Wikidata: Q81989804
• Mol file: 1882-42-4.mol

Synonyms:4-tert-Butylpiperidine;1882-42-4;Piperidine, 4-(1,1-dimethylethyl)-;4-(tert-butyl)piperidine;4-t-butylpiperidine;4-tert-Butyl-piperidine;4-(1,1-Dimethylethyl)piperidine;7DZ9SC8WCC;EINECS 217-539-4;Piperidine, 4-tert-butyl-;UNII-7DZ9SC8WCC;4- tert -Butyl-piperidine;SCHEMBL104705;DTXSID7062035;HMS1698G02;BAA88242;4-tert-Butyl-piperidine, AldrichCPR;MFCD00800914;AKOS000519289;AT27372;CCG-358804;BS-13249;BB 0260431;CS-0528908;FT-0707721;EN300-60666;F8880-4797;Z336079930;419571-25-8

Chemical Property of 4-tert-Butylpiperidine

Chemical Property:

• Vapor Pressure: 0.931mmHg at 25°C
• Boiling Point: 179.7°Cat760mmHg
• Flash Point: 54.9°C
• PSA: 12.03000
• Density: 0.837g/cm³
• LogP: 2.36090
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 141.151749610
• Heavy Atom Count: 10
• Complexity: 95.8

Purity/Quality:

98% ^*data from raw suppliers

4-tert-Butylpiperidine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)C1CCNCC1

Technology Process of 4-tert-Butylpiperidine

There total 8 articles about 4-tert-Butylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-tert-butylpyridine (3978-81-2) → 4-tert-butylpiperidine (1882-42-4)

Guidance literature:

With hydrogen; rhodium on alumina;

DOI:10.1016/S0040-4039(00)91562-4

Reference yield: 97.0%

4-(tert-butyl)piperidine hydrochloride (69682-13-9) → 4-tert-butylpiperidine (1882-42-4)

Guidance literature:

With sodium hydroxide; In diethyl ether; water;

DOI:10.1016/j.tet.2014.04.047

Reference yield: 81.5%

4-(tert-butyl)pyridin-1-ium chloride (65520-02-7) → 4-tert-butylpiperidine (1882-42-4)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethanol; for 24h; under 2280 Torr;

DOI:10.1007/BF00799561

upstream raw materials:

4-tert-butylpyridine

4-(tert-butyl)pyridin-1-ium chloride

4-(tert-butyl)-2-methylpyridine

phenyl 4-tert-butylpiperidine-1-carboxylate

Downstream raw materials:

4-tert-butyl-2,4,6-triisopropylbenzopiperidide

3-cyano-2-ethoxy-5-formyl-4-phenyl-6-(4-tert-butylpiperidino)pyridine

N-phenylacetyl-4-t-butyl-2-methoxypiperidine

C₁₇H₂₆NO₂⁽¹⁺⁾*FO₃S^(1-)

Refernces

• 1、 House,H.O. et al.. "". . p. 1073 - 1079. Retrieved 1966.
• 2、 Goessinger,E.. "-". . p. 339. Retrieved 1982.
• 3、 -. "BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY". Paragraph 0183. . Retrieved 2015/06/25.