Benzocyclobutene-4-boronic acid

Base Information

• Chemical Name: Benzocyclobutene-4-boronic acid
• CAS No.: 195730-31-5
• Molecular Formula: C8H9BO2
• Molecular Weight: 147.969
• Hs Code.: 2931900090
• Mol file: 195730-31-5.mol

Synonyms:Bicyclo[4.2.0]octa-1,3,5-trien-3-ylboronic acid;

Chemical Property of Benzocyclobutene-4-boronic acid

Chemical Property:

• Appearance/Colour: yellow or brown particles
• Vapor Pressure: 7.63E-05mmHg at 25°C
• Refractive Index: 1.587
• Boiling Point: 328.5 °C at 760 mmHg
• PKA: 8.88±0.20(Predicted)
• Flash Point: 152.5 °C
• PSA: 40.46000
• Density: 1.22 g/cm³
• LogP: -0.14980
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

Benzocyclobutene-4-boronic acid 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzocyclobutene-4-boronic acid

There total 1 articles about Benzocyclobutene-4-boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

4-bromobenzocyclobutene (1073-39-8) → 4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid (195730-31-5)

Guidance literature:

4-bromobenzocyclobutene; With magnesium; In tetrahydrofuran;

With Trimethyl borate; In tetrahydrofuran; at -78 - 20 ℃;

Reference yield: 85.0%

2,7-dibromo-9,9-bis(4-hexyloxyphenyl)fluorene + 4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid (195730-31-5) → C53H54O2

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In toluene; at 75 ℃; for 12h; Inert atmosphere;

DOI:10.1039/c4ra05898d

Reference yield: 60.0%

1-bromo-3,5-dichlorobenzene (19752-55-7) + 4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid (195730-31-5) → C14H10Cl2

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In water; toluene; at 90 ℃; for 12h; Inert atmosphere;

DOI:10.1016/j.polymer.2014.07.001

upstream raw materials:

4-bromobenzocyclobutene

Refernces