biphenyl-2-yl(diphenyl)methanol

Base Information

• Chemical Name: biphenyl-2-yl(diphenyl)methanol
• CAS No.: 6326-62-1
• Molecular Formula: C25H20O
• Molecular Weight: 336.433
• Mol file: 6326-62-1.mol

Synonyms:

Chemical Property of biphenyl-2-yl(diphenyl)methanol

Chemical Property:

• Vapor Pressure: 7.05E-12mmHg at 25°C
• Boiling Point: 525.7°Cat760mmHg
• Flash Point: 199.9°C
• Density: 1.138g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of biphenyl-2-yl(diphenyl)methanol

There total 20 articles about biphenyl-2-yl(diphenyl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

benzophenone (119-61-9) + 2-Bromobiphenyl (2052-07-5) → (biphenyl-2-yl)(diphenyl)methanol (6326-62-1)

Guidance literature:

2-Bromobiphenyl; With magnesium; In tetrahydrofuran; for 0.5h; Heating;

benzophenone; With lithium chloride; In tetrahydrofuran; for 15h; Further stages.; Heating;

DOI:10.1016/j.tet.2008.07.021

Reference yield:

iodobenzene (591-50-4) + diethyl ether (60-29-7,927820-24-4) + phenyllithium (591-51-5) → triphenylmethyl alcohol (76-84-6) + (biphenyl-2-yl)(diphenyl)methanol (6326-62-1)

Guidance literature:

anschliessende Umsetzung mit Benzophenon;

Reference yield:

benzophenone (119-61-9) + 2,2'-dibromobiphenyl (13029-09-9) → 2-bromo-2'-((hydroxyl)diphenylmethyl)biphenyl (1059502-44-1) + (biphenyl-2-yl)(diphenyl)methanol (6326-62-1)

Guidance literature:

2,2'-dibromobiphenyl; With n-butyllithium; In tetrahydrofuran; hexane; at 0 ℃;

benzophenone; In tetrahydrofuran; hexane; at 0 ℃;

DOI:10.1021/ol8015572

upstream raw materials:

benzophenone

4-biphenyllithium

fluorobenzene

diethyl ether

Downstream raw materials:

9,9-diphenylfluorene

2-methylbiphenyl

2-Biphenylyldiphenylmethylazid

4-tritylphenol

Refernces

• 1、 Nagaki, Aiichiro,Takabayashi, Naofumi,Tomida, Yutaka,Yoshida, Jun-ichi. "Selective monolithiation of dibromobiaryls using microflow systems". supporting information; experimental part. p. 3937 - 3940. Retrieved 2009/06/18.