4-Tritylphenol

Base Information

• Chemical Name: 4-Tritylphenol
• CAS No.: 978-86-9
• Molecular Formula: C25H20O
• Molecular Weight: 336.433
• Hs Code.: 2907199090
• European Community (EC) Number: 213-557-1
• NSC Number: 56593,39742
• DSSTox Substance ID: DTXSID8075172
• Nikkaji Number: J236.706H
• Wikidata: Q82003196
• ChEMBL ID: CHEMBL1795581
• Mol file: 978-86-9.mol

Synonyms:4-Tritylphenol;978-86-9;4-Triphenylmethylphenol;4-(Triphenylmethyl)phenol;p-Triphenylmethylphenol;Phenol, 4-(triphenylmethyl)-;C25H20O;4-Hydroxytetraphenylmethane;EINECS 213-557-1;AI3-61705;p-Cresol, .alpha.,.alpha.,.alpha.-triphenyl-;p-Tritylphenol;4-Tritylphenol, 97%;NCIOpen2_007452;4-[tri(phenyl)methyl]phenol;Phenol,4-(triphenylmethyl)-;4-(2-benzhydrylphenyl)phenol;SCHEMBL218636;YSCH0107;CHEMBL1795581;DTXSID8075172;NIPKXTKKYSKEON-UHFFFAOYSA-;NSC39742;NSC56593;C25-H20-O;MFCD00002364;NSC 39742;NSC 56593;NSC-39742;NSC-56593;STK374501;AKOS005447524;AS-56528;CS-0156532;FT-0633206;T1654;A845760

Chemical Property of 4-Tritylphenol

Chemical Property:

• Appearance/Colour: light yellow crystalline powder
• Vapor Pressure: 7.41E-10mmHg at 25°C
• Melting Point: 283-286 °C(lit.)
• Refractive Index: 1.638
• Boiling Point: 480.5 °C at 760 mmHg
• PKA: 10.21±0.10(Predicted)
• Flash Point: 224.9 °C
• PSA: 20.23000
• Density: 1.143 g/cm³
• LogP: 5.77490
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 6.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 336.151415257
• Heavy Atom Count: 26
• Complexity: 358

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Tritylphenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=C(C=C4)O
• Uses: 4-Tritylphenol was used in the synthesis of 5-arylethynyl-2′-deoxyuridines and propargyl ethers. It may be used in the synthesis of pyridyl rotaxane.

Technology Process of 4-Tritylphenol

There total 35 articles about 4-Tritylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.4%

triphenylmethyl alcohol (76-84-6) + phenol (108-95-2,27073-41-2) → 4-tritylphenol (978-86-9)

Guidance literature:

With aluminium(III) phenoxide; In various solvent(s); at 100 ℃; for 4h;

Reference yield: 91.0%

[4-(triphenylmethyl)phenoxy]acetic acid (162456-86-2) → 4-tritylphenol (978-86-9)

Guidance literature:

[4-(triphenylmethyl)phenoxy]acetic acid; With triethylamine; In N,N-dimethyl-formamide; toluene; for 3h; Heating;

With potassium hydroxide; glycerol; In ethanol; N,N-dimethyl-formamide; toluene; for 2h; Further stages.; Heating;

DOI:10.1002/ejoc.200700769

Reference yield: 63.0%

Phenyl-trityl-amine (4471-22-1) + phenol (108-95-2,27073-41-2) → 4-tritylphenol (978-86-9) + 4-tritylaniline (22948-06-7)

Guidance literature:

With aniline hydrochloride; Heating;

upstream raw materials:

diethyl ether

trityl phenoxide

(4-methoxyphenyl)triphenylmethane

(biphenyl-2-yl)(diphenyl)methanol

Downstream raw materials:

biphenyl

4-Phenylphenol

benzhydryl methyl ether

4-(Methoxy-phenyl-methyl)-phenol

Refernces

• 1、 Camaj, David,Carlsson, Robin,Dalla-Santa, Oscar,Lill, Malin,Lundberg, Helena,Margarita, Cristiana,Ramstr?m, Anja,Tu?on, Hernando,Villo, Piret. "Zirconium-catalysed direct substitution of alcohols: enhancing the selectivity by kinetic analysis". . p. 7420 - 7430. Retrieved 2021/11/23.
• 2、 Zhang, Dawei,Ronson, Tanya K.,Güryel, Songül,Thoburn, John D.,Wales, David J.,Nitschke, Jonathan R.. "Temperature Controls Guest Uptake and Release from Zn4L4 Tetrahedra". supporting information. p. 14534 - 14538. Retrieved 2019/10/11.