N-(TRIPHENYLMETHYL)ANILINE

Base Information

• Chemical Name: N-(TRIPHENYLMETHYL)ANILINE
• CAS No.: 4471-22-1
• Molecular Formula: C25H21N
• Molecular Weight: 335.448
• Hs Code.: 2921420090
• Mol file: 4471-22-1.mol

Synonyms:Benzenamine, N-(triphenylmethyl)-;N-(Triphenylmethyl)aniline;Phenyltriphenylmethylamine;

Chemical Property of N-(TRIPHENYLMETHYL)ANILINE

Chemical Property:

• Vapor Pressure: 6.74E-09mmHg at 25°C
• Melting Point: 148-149 °C
• Refractive Index: 1.653
• Boiling Point: 467 °C at 760 mmHg
• PKA: 2.45±0.50(Predicted)
• Flash Point: 249.2 °C
• PSA: 12.03000
• Density: 1.13 g/cm³
• LogP: 6.16360

Purity/Quality:

98%Min ^*data from raw suppliers

N-Tritylaniline ^*data from reagent suppliers

Safty Information:

• Safety Statements: S22:Do not inhale dust.; S24/25:Avoid contact with skin and eyes.

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(TRIPHENYLMETHYL)ANILINE

There total 21 articles about N-(TRIPHENYLMETHYL)ANILINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

trityl chloride (76-83-5) + aniline (62-53-3) → Phenyl-trityl-amine (4471-22-1)

Guidance literature:

trityl chloride; aniline; at 190 ℃; for 0.5h;

With hydrogenchloride; In methanol; for 0.5h; Reflux;

DOI:10.1002/anie.201307340

Reference yield: 81.0%

triphenylmethyl alcohol (76-84-6) + aniline (62-53-3) → Phenyl-trityl-amine (4471-22-1)

Guidance literature:

With zinc(II) chloride; In dichloromethane; at 20 ℃; for 0.25h;

DOI:10.1080/00304948.2020.1716617

Reference yield: 65.0%

4-dimethylamino-1-N-(triphenylmethyl)pyridinium chloride (78646-25-0) + aniline (62-53-3) → Phenyl-trityl-amine (4471-22-1)

Guidance literature:

With C₅₁H₃₉N₁₅O₃; In dichloromethane; for 36h; Reagent/catalyst;

DOI:10.1039/d0cy01090a

upstream raw materials:

diethyl ether

N-(diphenylmethylidene)phenylamine

phenylpotassium

phenylcalcium iodide

Downstream raw materials:

triphenylmethyl alcohol

Triphenylmethylamin

4-tritylphenol

4-tritylaniline

Refernces

• 1、 Gupta, Shruti,Khurana, Jitender M.,Singh, Ashima. "Zinc Chloride Mediated Nucleophilic Substitution: Amination and Thioetherification of Alcohols at Room Temperature". . . Retrieved 2020/03/30.
• 2、 Zhang, Muwei,Chen, Ying-Pin,Bosch, Mathieu,Gentle III, Thomas,Wang, Kecheng,Feng, Dawei,Wang, Zhiyong U.,Zhou, Hong-Cai. "Symmetry-guided synthesis of highly porous metal-organic frameworks with fluorite topology". supporting information. p. 815 - 818. Retrieved 2014/01/23.