Phosphine oxide, tris(p-chlorophenyl)-

Base Information

• Chemical Name: Phosphine oxide, tris(p-chlorophenyl)-
• CAS No.: 4576-56-1
• Molecular Formula: C18H12Cl3OP
• Molecular Weight: 381.625
• Hs Code.: 2903999090
• NSC Number: 10066
• UNII: 2EVV6SBP6A
• DSSTox Substance ID: DTXSID40196613
• Nikkaji Number: J50.224C
• Wikidata: Q83069642
• Mol file: 4576-56-1.mol

Synonyms:4576-56-1;Phosphine oxide, tris(p-chlorophenyl)-;Tris(p-chlorophenyl)phosphine oxide;TRI(4-CHLOROPHENYL)PHOSPHINE OXIDE;Phosphine oxide, tris(4-chlorophenyl)-;1-bis(4-chlorophenyl)phosphoryl-4-chlorobenzene;Tri(4-chlorophenyl)phosphineoxide;Tris(4-chlorophenyl)phosphine oxide;NSC 10066;BRN 2814673;C18H12Cl3OP;NSC-10066;tris(4-chlorophenyl)phosphineoxide;2EVV6SBP6A;SCHEMBL1000520;C18-H12-Cl3-O-P;WLN: GR DPO&R DG&R DG;DTXSID40196613;NSC10066;tris-(p-chlorophenyl) phosphine oxide;LS-106049;CS-0203256

Chemical Property of Phosphine oxide, tris(p-chlorophenyl)-

Chemical Property:

• Vapor Pressure: 1.5E-10mmHg at 25°C
• Melting Point: 176oC
• Boiling Point: 524°Cat760mmHg
• Flash Point: 270.7°C
• PSA: 26.88000
• Density: 1.41g/cm³
• LogP: 5.28620
• XLogP3: 5.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 379.969135
• Heavy Atom Count: 23
• Complexity: 358

Purity/Quality:

99% ^*data from raw suppliers

TRIS(4-CHLOROPHENYL)PHOSPHINE OXIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1P(=O)(C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)Cl)Cl

Technology Process of Phosphine oxide, tris(p-chlorophenyl)-

There total 20 articles about Phosphine oxide, tris(p-chlorophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

tri(4-chlorophenyl)phosphine (1159-54-2) → tris(p-chlorophenyl)phosphine oxide (4576-56-1)

Guidance literature:

With sulfur trioxide; In dichloromethane; at 0 ℃;

DOI:10.1021/jo00158a034

Reference yield: 35.0%

bromochlorobenzene (106-39-8) + tetrakis(hydroxymethyl)phosphonium chloride (124-64-1) → tris(p-chlorophenyl)phosphine oxide (4576-56-1) + bis(4-chlorophenyl)methylphosphine oxide (54844-85-8)

Guidance literature:

With 3 A molecular sieve; potassium carbonate; [(o-Tol)2PC₆H₄CH₂Pd(OAc)]2; In N,N-dimethyl acetamide; at 130 ℃; for 17h;

DOI:10.1080/00397910008087212

Reference yield: 34.0%

tris-p-chlorophenylphosphine sulphide (5032-62-2) → tris(p-chlorophenyl)phosphine oxide (4576-56-1)

Guidance literature:

With 2-methyl-3-p-nitrophenyloxaziridine; In chloroform-d1; at 40 ℃; for 72h; Irradiation;

upstream raw materials:

diethyl chlorophosphate

(4-chlorphenyl)magnesium bromide

4-chlorophenylmagnesium iodide

tri(4-chlorophenyl)phosphine

Downstream raw materials:

(E)-[4-chloro-2-(1,2-diphenylethenyl)phenyl]bis(4-chlorophenyl)phosphine oxide

[Rh(CO)(OP(ClC₆H₄)3)(P(C₆H₅)3)2]⁽¹⁺⁾*ClO₄^(1-)=[Rh(CO)(OP(ClC₆H₄)3)(P(C₆H₅)3)2]ClO₄

[Rh(CO)2(OP(ClC₆H₄)3)2]⁽¹⁺⁾*ClO₄^(1-)=[Rh(CO)2(OP(ClC₆H₄)3)2]ClO₄

tri(4-chlorophenyl)phosphine

Refernces

• 1、 -. "Organic super-long room-temperature phosphorescent material as well as preparation method and application thereof". Paragraph 0035; 0038-0040. . Retrieved 2021/06/12.
• 2、 Sadeghzadeh, Seyed Mohsen,Zhiani, Rahele. "Photooxidation of triarylphosphines under aerobic conditions in the presence of a gold(iii) complex on cellulose extracted from Carthamus tinctorius immobilized on nanofibrous phosphosilicate". . p. 1509 - 1516. Retrieved 2019/01/24.