Sedoheptulose 7-phosphate

Base Information

• Chemical Name: Sedoheptulose 7-phosphate
• CAS No.: 2646-35-7
• Molecular Formula: C₇H₁₅O₁₀P
• Molecular Weight: 290.164
• Nikkaji Number: J604.570G
• Wikipedia: Sedoheptulose_7-phosphate
• Wikidata: Q3040325
• Metabolomics Workbench ID: 50236
• Mol file: 2646-35-7.mol

Synonyms:D-altro-2-heptulose, 7-(dihydrogen phosphate);heptulose-7-phosphate;sedoheptulose 7-phosphate

Chemical Property of Sedoheptulose 7-phosphate

Chemical Property:

• Vapor Pressure: 4.61E-26mmHg at 25°C
• Boiling Point: 751.4°Cat760mmHg
• PKA: 1.83±0.10(Predicted)
• Flash Point: 408.3°C
• PSA: 192.61000
• Density: 1.862g/cm³
• LogP: -2.86550
• Storage Temp.: ?20°C
• XLogP3: -5
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 8
• Exact Mass: 290.04028367
• Heavy Atom Count: 18
• Complexity: 313

Purity/Quality:

99%, ^*data from raw suppliers

D-Sedoheptulose-7-phosphate barium salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(C(C(C(=O)CO)O)O)O)O)OP(=O)(O)O
• Isomeric SMILES: C([C@H]([C@H]([C@H]([C@@H](C(=O)CO)O)O)O)O)OP(=O)(O)O

Technology Process of Sedoheptulose 7-phosphate

There total 2 articles about Sedoheptulose 7-phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-erythrulose (533-50-6) + D-ribose 5-phosphate (3615-55-2,7591-07-3,13137-52-5,66768-39-6,69881-36-3,69881-39-6,136376-80-2,136376-83-5,136376-85-7,136376-88-0,136376-89-1,4300-28-1) → D-sedoheptulose-7-phosphate (69975-90-2,90196-61-5,2646-35-7) + Glyceraldehyde (56-82-6,367-47-5,26793-98-6)

Guidance literature:

With transketolase from geobacillus stearothermophilus; thiamine diphosphate; 1-butyl-3-methylimidazolium chloride; magnesium chloride; In aq. buffer; at 27 ℃; pH=7.5; Enzymatic reaction;

DOI:10.1002/cctc.201500524

Reference yield:

L-erythrulose (533-50-6) + D-ribose 5-phosphate (3615-55-2,7591-07-3,13137-52-5,66768-39-6,69881-36-3,69881-39-6,136376-80-2,136376-83-5,136376-85-7,136376-88-0,136376-89-1,4300-28-1) → D-sedoheptulose-7-phosphate (69975-90-2,90196-61-5,2646-35-7) + Glycolaldehyde (141-46-8)

Guidance literature:

With thiamine diphosphate; NADH; magnesium chloride; yeast alcohol dehydrogenase; In glycylglycine buffer; pH=7.5; Reagent/catalyst; Kinetics; Enzymatic reaction;

DOI:10.1002/adsc.201000925

Reference yield:

D-sedoheptulose-7-phosphate (69975-90-2,90196-61-5,2646-35-7) → 2-epi-5-epi-valiolone (244195-43-5)

Guidance literature:

With potassium fluoride; 6XHis-(Nonomuraea spiralis IMC A?0156 2-epi-5-epi-valiolone synthase PrlA) fusion protein; NAD; cobalt(II) chloride; In aq. phosphate buffer; at 30 ℃; for 2h; pH=7.5; Enzymatic reaction;

DOI:10.1021/np400159a

upstream raw materials:

L-erythrulose

D-ribose 5-phosphate

Downstream raw materials:

2-epi-valiolone

2-epi-5-epi-valiolone

ADP-D-glycero-β-D-manno-heptose

Refernces

• 1、 Abdoul-Zabar, Juliane,Sorel, Isabelle,Helaine, Virgil,Charmantray, Franck,Devamani, Titu,Yi, Dong,De Berardinis, Veronique,Louis, Dominique,Marliere, Philippe,Fessner, Wolf-Dieter,Hecquet, Laurence. "Thermostable transketolase from Geobacillus stearothermophilus: Characterization and catalytic properties". . p. 116 - 128. Retrieved 2013/03/13.