1,6-di-O-phosphono-beta-D-fructofuranose

Base Information

• Chemical Name: 1,6-di-O-phosphono-beta-D-fructofuranose
• CAS No.: 34693-15-7
• Deprecated CAS: 125740-83-2,4937-84-2,77-82-7
• Molecular Formula: C6H14O12P2
• Molecular Weight: 340.117
• European Community (EC) Number: 207-683-6
• UNII: WCH874XLB1
• DSSTox Substance ID: DTXSID0048347
• Nikkaji Number: J322.162H
• Wikipedia: Fructose_1,6-bisphosphate
• Wikidata: Q414945
• Metabolomics Workbench ID: 51556
• ChEMBL ID: CHEMBL97893
• Mol file: 34693-15-7.mol

Synonyms:fructose 1,6-bisphosphate;fructose 1,6-diphosphate;fructose-1,6-diphosphate;fructose-1,6-diphosphate magnesium salt;fructose-1,6-diphosphate, (alpha-D)-isomer;fructose-1,6-diphosphate, (beta-D)-isomer;fructose-1,6-diphosphate, (L)-isomer;fructose-1,6-diphosphate, 2-(18)O-labeled;fructose-1,6-diphosphate, barium (1:2) salt;fructose-1,6-diphosphate, calcium (1:2) salt;fructose-1,6-diphosphate, calcium salt;fructose-1,6-diphosphate, disodium salt;fructose-1,6-diphosphate, monosodium salt;fructose-1,6-diphosphate, sodium salt, monohydrate;fructose-1,6-diphosphate, tetrapotassium salt;fructose-1,6-diphosphate, tetrasodium salt;fructose-1,6-diphosphate, trisodium salt;Sr-FDP;strontium fructose 1,6-diphosphate;strontium fructose-1,6-diphosphate

Chemical Property of 1,6-di-O-phosphono-beta-D-fructofuranose

Chemical Property:

• Boiling Point: 722.6°Cat760mmHg
• Flash Point: 390.8°C
• PSA: 223.06000
• Density: 2.095g/cm³
• LogP: -2.98580
• Storage Temp.: -20°C
• XLogP3: -5.6
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 6
• Exact Mass: 339.99604987
• Heavy Atom Count: 20
• Complexity: 428

Purity/Quality:

Anti-Fubp1 antibody produced in goat affinity isolated antibody, buffered aqueous solution ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C1C(C(C(O1)(COP(=O)(O)O)O)O)O)OP(=O)(O)O
• Isomeric SMILES: C([C@@H]1[C@H]([C@@H]([C@](O1)(COP(=O)(O)O)O)O)O)OP(=O)(O)O
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Technology Process of 1,6-di-O-phosphono-beta-D-fructofuranose

There total 5 articles about 1,6-di-O-phosphono-beta-D-fructofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

→ fructose 1,6-diphosphate (34693-15-7)

Guidance literature:

With phosphofructokinase; Tris (0.1 M, pH 7.6); ATP; magnesium chloride; hexokinase; for 24h; Ambient temperature;

DOI:10.1021/jo00168a023

Reference yield:

fructofuranose 1,6-bisphosphate (717817-28-2) → α-D-fructofuranose 1,6-diphosphate (34693-23-7) + fructose 1,6-diphosphate (34693-15-7) + fructose-1,6-bisphosphate (488-69-7,55529-38-9,87932-52-3)

Guidance literature:

In water; water-d2; Rate constant; by NMR method;

DOI:10.1021/ja00294a041

Reference yield:

dihydroxyacetone phosphate (57-04-5) + D-glyceraldehyde 3-phosphate (20283-52-7) → L-Sorbose 1,6-bis(phosphate) (77-82-7,6915-27-1,34693-15-7,34693-23-7,148219-43-6,148219-45-8)

Guidance literature:

With aldolase;

DOI:10.1021/jo00167a012

upstream raw materials:

D-fructose-6-phosphoric acid

fructofuranose 1,6-bisphosphate

D-glucose

dihydroxyacetone phosphate

Downstream raw materials:

5-deoxy-D-threo-pent-2-ulose 1-phosphate

D-2-deoxyribose

L-α-Phosphatidic acid

D-glyceraldehyde-3-phosphate

Refernces

• 1、 Enomoto, Toshiki,Ohyama, Hideo,Kodama, Miyuki. "Purification and Characterization of Pyrophosphate: D-Fructose 6-Phosphate 1-Phosphotransferase from Rice Seedlings". . p. 251 - 255. Retrieved 2007/10/02.
• 2、 Wong, Chi-Huey,Mazenod, Francois P.,Whitesides, George M.. "Chemical and Enzymatic Syntheses of 6-Deoxyhexoses. Conversion to 2,5-Dimethyl-4-hydroxy-2,3-dihydrofuran-3-one (Furaneol) and Analogues". . p. 3493 - 3497. Retrieved 2007/10/02.