Etofenprox

Base Information

• Chemical Name: Etofenprox
• CAS No.: 80844-07-1
• Molecular Formula: C25H28O3
• Molecular Weight: 376.496
• European Community (EC) Number: 407-980-2,617-179-1
• UNII: 0LD7P9153C
• DSSTox Substance ID: DTXSID9032610
• Nikkaji Number: J33.917B
• Wikipedia: Etofenprox
• Wikidata: Q2415193
• NCI Thesaurus Code: C65587
• Metabolomics Workbench ID: 56254
• ChEMBL ID: CHEMBL2105573
• Mol file: 80844-07-1.mol

Synonyms:2-(4-ethoxyphenyl)-2-methylpropyl-3-phenoxybenzyl ether;ethofenprox;etofenprox;Trebon

Chemical Property of Etofenprox

Chemical Property:

• Appearance/Colour: white solid
• Vapor Pressure: 5.75E-09mmHg at 25°C
• Melting Point: 36oC
• Refractive Index: 1.559
• Boiling Point: 481.6±40.0 °C at 760 mmHg
• Flash Point: 165.1±24.6 °C
• PSA: 27.69000
• Density: 1.1±0.1 g/cm³
• LogP: 6.37200
• Storage Temp.: 0-6°C
• Water Solubility.: <0.001 mg l-1(25 °C)
• XLogP3: 7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 9
• Exact Mass: 376.20384475
• Heavy Atom Count: 28
• Complexity: 422

Purity/Quality:

99% ^*data from raw suppliers

Etofenprox ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3
• Description: Etofenprox belongs to a pyrethroid derivative that is commonly used as an insecticide in agriculture, horticulture, viticulture, forestry, animal health and public health against various insect pests. It can be found as an active ingredient in a variety of pest control products, which is effective to control broad spectrum of pests, such as crawling and flying insects. In the field of agriculture, etofenprox can be applied on a broad range of crops, including rice, fruits, vegetables, corn, soybeans and tea, which is poorly absorbed by roots and little translocation occurs within plants. It is also used for the public health by controlling adult mosquitoes, non biting midges, biting and non-biting flies, which may carry the pathogen. Besides, etofenprox can be found as an component in flea and tick medications for dogs and cats. Etofenprox is a new type of insecticide with low mammalian toxicity, which can be decomposed in soil by anaerobic and aerobic microorganisms. It functions by strongly disrupting the transmission of nervous impulses and causes paralysis and death to the target insect.
• Uses: Insecticide. Etofenprox is used to control a wide variety of insects on fruit, tea, soyabeans and many vegetables. It is also used in public health and animal health.

Technology Process of Etofenprox

There total 13 articles about Etofenprox which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3-phenoxybenzyl bromide (51632-16-7) + 2-(4-ethoxyphenyl)-2,2-dimethylethanol (83493-63-4) → etofenprox (80844-07-1)

Guidance literature:

With potassium hydroxide; tetra-(n-butyl)ammonium iodide; In tetrahydrofuran; for 0.583333h; Irradiation;

Reference yield: 93.0%

(m-phenoxyphenyl)methyl chlorosulfite + 2-(4-ethoxyphenyl)-2,2-dimethylethanol (83493-63-4) → etofenprox (80844-07-1)

Guidance literature:

at 50 ℃; for 2h;

Reference yield: 86.0%

ethyl iodide (75-03-6) + 3-phenoxybenzyl 2-(4-hydroxyphenyl)-2-methylpropyl ether (80854-21-3) → etofenprox (80844-07-1)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 0 - 25 ℃; for 14h; Inert atmosphere;

DOI:10.3390/molecules24061023

upstream raw materials:

3-phenoxybenzyl bromide

2-(4-ethoxyphenyl)-2,2-dimethylethanol

3-Phenoxybenzyl alcohol

4-(2'-chloro-1',1'-dimethylethyl)ethoxybenzene

Refernces

• 1、 -. "Preparation method of ethofenprox". Paragraph 0034; 0036; 0037; 0039; 0040; 0042;. . Retrieved 2017/08/27.
• 2、 Galin,Rakhimov,Vyrypaev,Bogdanov,Amirkhanov,Furlei,Tolstikov. "Synthesis of ethophenprox analogs". . p. 826 - 835. Retrieved 2007/10/03.