L-canavanine

Base Information

• Chemical Name: L-canavanine
• CAS No.: 543-38-4
• Molecular Formula: C₅H₁₂N₄O₃
• Molecular Weight: 176.175
• Hs Code.: 2925290090
• European Community (EC) Number: 624-714-2
• UNII: 3HZV514J4B
• DSSTox Substance ID: DTXSID5045041
• Nikkaji Number: J9.236C
• Wikipedia: Canavanine
• Wikidata: Q418408
• Metabolomics Workbench ID: 38191
• ChEMBL ID: CHEMBL443732
• Mol file: 543-38-4.mol

Synonyms:Canavanine

Chemical Property of L-canavanine

Chemical Property:

• Vapor Pressure: 1.21E-08mmHg at 25°C
• Melting Point: 184°
• Refractive Index: 1.7900 (estimate)
• Boiling Point: 431.2°Cat760mmHg
• PKA: pK1: 2.50(+2);pK2: 6.60(+1);pK3: 9.25(0) (25°C)
• Flash Point: 214.6°C
• PSA: 134.45000
• Density: 1.61g/cm³
• LogP: 0.09430
• Storage Temp.: 2-8°C
• Solubility.: H2O: <100 mg/mL
• XLogP3: -4.8
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 176.09094026
• Heavy Atom Count: 12
• Complexity: 178

Purity/Quality:

98%,99%, ^*data from raw suppliers

L-Canavanine ≥98% (TLC), powder, from Canavalia ensiformis ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22
• Safety Statements: 36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Biological Agents -> Amino Acids and Derivatives
• Canonical SMILES: C(CON=C(N)N)C(C(=O)O)N
• Isomeric SMILES: C(CON=C(N)N)[C@@H](C(=O)O)N
• Uses: NO synthase inhibitor

Technology Process of L-canavanine

There total 1 articles about L-canavanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-isourea (2440-60-0) → l-canavanine (543-38-4,13269-28-8)

Guidance literature:

With methanol; at 20 ℃; Kochen des Reaktionsprodukts mit 10prozentig.wss.HCl;

Reference yield:

l-canavanine (543-38-4,13269-28-8) → l-canaline (496-93-5) + urea (57-13-6)

Guidance literature:

durch Einwirkung von Arginase-Praeparaten aus Schweineleber;

DOI:10.1017/S0317167100002043

Reference yield:

l-canavanine (543-38-4,13269-28-8) → urea (57-13-6)

Guidance literature:

Arginase-Praeparate aus Schweineleber;

DOI:10.1017/S031716710000202X DOI:10.1017/S0317167100002043

upstream raw materials:

2-methyl-isourea

Downstream raw materials:

O-ureido-L-homoserine

l-canaline

urea

DL-Homoserine