Dodecanoic acid, 1-phenylethyl ester

Base Information

• Chemical Name: Dodecanoic acid, 1-phenylethyl ester
• CAS No.: 97130-78-4
• Molecular Formula: C20H32O2
• Molecular Weight: 304.473
• Mol file: 97130-78-4.mol

Synonyms:

Chemical Property of Dodecanoic acid, 1-phenylethyl ester

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Dodecanoic acid, 1-phenylethyl ester

There total 3 articles about Dodecanoic acid, 1-phenylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

lauric acid (143-07-7) + ethylbenzene (100-41-4,27536-89-6) → (R,S)-1-phenylethyl laurate (97130-78-4)

Guidance literature:

With tetra-(n-butyl)ammonium iodide; In water; at 80 ℃; for 8h;

DOI:10.1002/adsc.201100920

Reference yield:

n-dodecanoyl chloride (112-16-3) + 1-Phenylethanol (98-85-1,13323-81-4) → (R,S)-1-phenylethyl laurate (97130-78-4)

Guidance literature:

With pyridine; In diethyl ether; at 0 - 20 ℃; for 24h;

DOI:10.1016/j.crci.2016.05.002

Reference yield:

lauric acid (143-07-7) + 1-Phenylethanol (98-85-1,13323-81-4) → (R,S)-1-phenylethyl laurate (97130-78-4)

Guidance literature:

With cysteine mutant TALipB; In hexane; at 40 ℃; for 12h; Reagent/catalyst; Enzymatic reaction;

DOI:10.1016/j.bbrc.2016.01.189

upstream raw materials:

lauric acid

ethylbenzene

n-dodecanoyl chloride

1-Phenylethanol

Downstream raw materials:

(S)-1-phenylethanol

(R)-1-phenylethanol

(R)-1-phenylethyl dodecanoate

Refernces

• 1、 Razi, Samra,Zeror, Saoussen,Merabet-Khelassi, Mounia,Kolodziej, Emilie,Toffano, Martial,Aribi-Zouioueche, Louisa. "Two Approaches for CAL-B-Catalyzed Enantioselective Deacylation of a Set of α-Phenyl Ethyl Esters: Organic Solvent with Sodium Carbonate and Micro-aqueous Medium". . p. 2603 - 2611. Retrieved 2021/01/15.
• 2、 Feng, Jie,Liang, Shuai,Chen, Shan-Yong,Zhang, Ji,Fu, Song-Sen,Yu, Xiao-Qi. "A metal-free oxidative esterification of the benzyl C-H bond". experimental part. p. 1287 - 1292. Retrieved 2012/06/15.