Dodecanoic acid, (1R)-1-phenylethyl ester

Base Information

• Chemical Name: Dodecanoic acid, (1R)-1-phenylethyl ester
• CAS No.: 116644-59-8
• Molecular Formula: C20H32O2
• Molecular Weight: 304.473
• Mol file: 116644-59-8.mol

Synonyms:

Chemical Property of Dodecanoic acid, (1R)-1-phenylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Dodecanoic acid, (1R)-1-phenylethyl ester

There total 11 articles about Dodecanoic acid, (1R)-1-phenylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

vinyl laurate (2146-71-6) + 1-Phenylethanol (98-85-1,13323-81-4) → (S)-1-phenylethanol (1445-91-6) + (R)-1-phenylethyl dodecanoate (116644-59-8)

Guidance literature:

With Pseudomonas cepacia lipase; In diethyl ether; at 40 ℃; for 24h; enantioselective reaction; Enzymatic reaction;

DOI:10.1016/j.crci.2016.05.002

Reference yield: 22.0%

vinyl laurate (2146-71-6) + 1-Phenylethanol (98-85-1,13323-81-4) → (R)-1-phenylethyl dodecanoate (116644-59-8)

Guidance literature:

With air; H-beta zeolite CP₈₁₄E-22; Novozym(R) 435 lipase; In octane; water; at 60 ℃; for 5h;

DOI:10.1002/chem.200400713

Reference yield:

(R,S)-1-phenylethyl laurate (97130-78-4) → (R)-1-phenylethanol (1517-69-7) + (R)-1-phenylethyl dodecanoate (116644-59-8) + (S)-1-phenylethyl dodecanoate

Guidance literature:

With Pseudomonas cepacia lipase; water; In diethyl ether; at 40 ℃; for 24h; pH=7; enantioselective reaction; Enzymatic reaction;

DOI:10.1016/j.crci.2016.05.002

upstream raw materials:

lauric acid

1-Phenylethanol

(R)-1-phenylethanol

vinyl laurate

Refernces

• 1、 Mori,Funasaki,Kobayashi,Okahata. "Reversible activity changes of a lipid-coated lipase for enantioselective esterification in supercritical fluoroform". . p. 1832 - 1833. Retrieved 2001.
• 2、 Tao, Hongwen,Hao, Xiaojiang,Liu, Jinggen,Ding, Jian,Fang, Yuchun,Gu, Qianqun,Zhu, Weiming. "Resin glycoside constituents of Ipomoea pes-caprae (beach morning glory)". . p. 1998 - 2003. Retrieved 2008.
• 3、 Razi, Samra,Zeror, Saoussen,Merabet-Khelassi, Mounia,Kolodziej, Emilie,Toffano, Martial,Aribi-Zouioueche, Louisa. "Two Approaches for CAL-B-Catalyzed Enantioselective Deacylation of a Set of α-Phenyl Ethyl Esters: Organic Solvent with Sodium Carbonate and Micro-aqueous Medium". . p. 2603 - 2611. Retrieved 2021/01/15.
• 4、 Louren?o, Nuno M.T.,Matias, Sara C.,Altas, Margarida C.,Fonseca, Luis P.. "Low-temperature enzymatic hydrolysis resolution in mini-emulsion media". . p. 810 - 816. Retrieved 2015/03/31.