Furaltadone

Base Information

• Chemical Name: Furaltadone
• CAS No.: 139-91-3
• Molecular Formula: C13H16N4O6
• Molecular Weight: 324.293
• Hs Code.: 2934992000
• DSSTox Substance ID: DTXSID4048016
• NCI Thesaurus Code: C83874
• ChEMBL ID: CHEMBL1622119
• Mol file: 139-91-3.mol

Synonyms:2-Oxazolidinone,5-(morpholinomethyl)-3-[(5-nitrofurfurylidene)amino]- (6CI,7CI,8CI);3-(5-Nitro-2-furfurylideneamino)-5-(4-morpholinomethyl)-2-oxazolidone;5-(N-Morpholinomethyl)-3-(5-nitrofurfurylideneamino)-2-oxazolidone;5-Morpholinomethyl-3-(5-nitrofurfurylidenamino)-2-oxazolidone;5-Morpholinomethyl-3-(5-nitrofurfurylideneamino)-2-oxazolidone;5-Morpholinomethyl-3-(5-nitrofurfurylideneamino)oxazolidone;Altabactina;Altafur;Anauran;F 150;Fur-Novo;Furantoina;Furazolin;Furazoline;Furitale;Furlate;Furlidon;Furmethonol;Ibifur;Medifuran;NF 260;NSC 42388;Nitraldone;Sepsinol;Ultrafur;Unifur;Valsyn;

Chemical Property of Furaltadone

Chemical Property:

• Appearance/Colour: Yellow crystalline solid
• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 206 °C (dec.)
• Refractive Index: 1.669
• Boiling Point: 461.4 °C at 760 mmHg
• PKA: pKa 5.0 (Uncertain)
• Flash Point: 232.8 °C
• PSA: 113.33000
• Density: 1.58 g/cm³
• LogP: 1.07370
• Storage Temp.: 2-8°C
• Solubility.: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 4
• Exact Mass: 324.10698424
• Heavy Atom Count: 23
• Complexity: 476

Purity/Quality:

99% ^*data from raw suppliers

Furaltadone ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn, Xi
• Hazard Codes: Xn,Xi
• Statements: 22-36/37/38
• Safety Statements: 3-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1COCCN1CC2CN(C(=O)O2)N=CC3=CC=C(O3)[N+](=O)[O-]
• Description: This nitrofuran derivative can be added to animal feed. It induced contact dermatitis in a farm employee.
• Uses: A metabolite of Nitrofuran in milk. Antibacterial Furaltadone is a metabolite of Nitrofuran in milk and an intermediate in the synthesis of AMOZ (A634600), a metabolite of Furaltadone Hydrochloride.
• Therapeutic Function: Antibacterial

Technology Process of Furaltadone

There total 5 articles about Furaltadone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-nitrofurane-2-carboxaldehyde (698-63-5) + 3-amino-5-(morpholinomethyl)oxazolidin-2-one (43056-63-9) → furaltadone (139-91-3)

Guidance literature:

With sulfuric acid; In propan-1-ol; water;

DOI:10.1007/BF00760829

Reference yield:

5-nitrofurane-2-carboxaldehyde (698-63-5) → furaltadone (139-91-3)

Guidance literature:

With hydrogenchloride;

Reference yield:

→ furaltadone (139-91-3)

Guidance literature:

Hydrazinopropanol, ClCO2Et, Furfuralverb.;

upstream raw materials:

5-nitrofurane-2-carboxaldehyde

3-amino-5-(morpholinomethyl)oxazolidin-2-one

Downstream raw materials:

3-amino-5-(morpholinomethyl)oxazolidin-2-one

Refernces

• 1、 -. "3-Imino-1,2,4-benzotriazine-1-oxides". . . Retrieved 2008/06/13.