43056-63-9

Basic information

• Product Name: 3-AMINO-5-MORPHOLINOMETHYL-2-OXAZOLIDINONE
• Synonyms: 3-AMINO-5-MORPHOLINO-METHYL-1,3-OXAZOLIDONE;3-AMINO-5-MORPHOLINOMETHYL-2-OXAZOLIDINONE;AMOZ;3-amino-5-(4-morpholinomethyl)oxazolidin-2-one;5-(4-morpholinmethyl)-3-amino-2-oxazolidinone;AMOZ,3-Amino-5-morpholinomethyl-2-oxazolidinone;3-Amino-5-morpholinomethyl-2-oxazolidinone AMOZ;3-Amino-5-morpholin-4-ylmethyl-oxazolidin-2-one(AMOZ)
• CAS NO: 43056-63-9
• Molecular Formula: C₈H₁₅N₃O₃
• Molecular Weight: 201.22
• EINECS: 256-068-9
• Product Categories: Amines;Heterocycles;Metabolites & Impurities
• Mol File: 43056-63-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 115-120 °C
• Boiling Point: 315.8 °C at 760 mmHg
• Flash Point: 144.8 °C
• Appearance: /
• Density: 1.281
• Vapor Pressure: 0.000428mmHg at 25°C
• Refractive Index: 1.536
• Storage Temp.: 0-6°C
• Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• PKA: 6.19±0.10(Predicted)
• BRN: 179765
• CAS DataBase Reference: 3-AMINO-5-MORPHOLINOMETHYL-2-OXAZOLIDINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-5-MORPHOLINOMETHYL-2-OXAZOLIDINONE(43056-63-9)
• EPA Substance Registry System: 3-AMINO-5-MORPHOLINOMETHYL-2-OXAZOLIDINONE(43056-63-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 43056-63-9(Hazardous Substances Data)

Usage

Uses

A metabolite of Furaltadone Hydrochloride Environmental contaminants; Food contaminants; Heat processing contaminants.

InChI:InChI=1/C8H15N3O3/c9-11-6-7(14-8(11)12)5-10-1-3-13-4-2-10/h7H,1-6,9H2

Upstream product

• 6270-19-5 4-(oxiran-2-ylmethyl)morpholine 
• 139-91-3 furaltadone 
• 17930-35-7 5-(morpholinomethyl)oxazolidin-2-one 

Downstream Products

• 183193-59-1 3<<(2-Nitrophenyl)methylene>amino>-5-morpholinomethyl-2-oxazolidinone 
• 30185-92-3 3-(5-nitro-1-methyl-2-imidazolyl)-methyleneamino-5-morpholinomethyl-2-oxazolidinone hydrochloride 
• 52279-59-1 (+/-)-3-<1-Methyl-5-nitro-imidazol-2-ylmethylen>-5-morpholinomethyl-oxazolidin-2-on 
• 59772-77-9 3-benzylideneamino-5-morpholin-4-ylmethyl-oxazolidin-2-one 
• 92026-95-4 3-<3,4-Dichlor-5-nitro-furfurylidenamino>-5-morpholinomethyl-oxazolidinon-(2) 
• 92297-09-1 5-morpholin-4-ylmethyl-3-[2-(5-nitro-furan-2-yl)-2-oxo-ethylideneamino]-oxazolidin-2-one 
• 3318-79-4 5-morpholin-4-ylmethyl-3-[3-(5-nitro-furan-2-yl)-allylideneamino]-oxazolidin-2-one 
• 139-91-3 furaltadone 

Relevant articles and documents

Preparation method of 3-hydrazino-5-morpholinomethyl-2-oxazolidinone

The invention provides a preparation method of 3-hydrazino-5-morpholinomethyl-2-oxazolidinone, and belongs to the technical field of chemical synthesis. The preparation method comprises the followingsteps: carrying out a cyclization reaction on 1-Boc protective hydrazine-3-morpholine-2-propanol and a carbonic ester substance to obtain 3-Boc protective hydrazine-5-morpholinomethyl-2-oxazolidinone;and finally hydrolyzing to obtain the AMOZ. The chemical structural formula of the 1-Boc protective hydrazine-3-morpholine-2-propanol is shown in the specification, the chemical structural formula ofthe 3-Boc protective hydrazine-5-morpholinomethyl-2-oxazolidinone is shown in the specification, and the chemical structural formula of the AMOZ is shown in the specification; and the carbonic estersubstance contains at least one of diethyl carbonate, dimethyl carbonate, di-tert-butyl decarbonate, and dipropyl carbonate. The method is simple in synthetic route, the AMOZ is synthesized by adopting a one-pot method, and the catalyst is used in the preparation process, so that the loss in the synthesis process is greatly reduced, the synthesis yield and the recovery rate are relatively high; and the method is suitable for mass production.

Cyclizative atmospheric CO2 fixation by unsaturated amines with t-BuOI leading to cyclic carbamates

A cyclizative atmospheric CO2 fixation by unsaturated amines such as allyl and propargyl amines under mild reaction conditions, efficiently leading to cyclic carbamates bearing a iodomethyl group, have been developed utilizing tert-butyl hypoiodite (t-BuOI).