2-BROMO-3'-CHLOROBENZOPHENONE

Base Information

• Chemical Name: 2-BROMO-3'-CHLOROBENZOPHENONE
• CAS No.: 99586-30-8
• Molecular Formula: C13H8BrClO
• Molecular Weight: 295.55900
• Hs Code.: 2914700090
• Mol file: 99586-30-8.mol

Synonyms:2-BROMO-3'-CHLOROBENZOPHENONE;2-Brom-3'-chlor-benzophenon;

Chemical Property of 2-BROMO-3'-CHLOROBENZOPHENONE

Chemical Property:

• Vapor Pressure: 3.29E-06mmHg at 25°C
• Boiling Point: 387.5oC at 760 mmHg
• Flash Point: 188.1oC
• PSA: 17.07000
• Density: 1.51g/cm3
• LogP: 4.33350

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-3'-chlorobenzophenone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-BROMO-3'-CHLOROBENZOPHENONE

There total 2 articles about 2-BROMO-3'-CHLOROBENZOPHENONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromobenzoic acid chloride (7154-66-7) + (3-chlorophenyl)magnesium bromide (36229-42-2) → 2-bromo-3'-chlorobenzophenone (99586-30-8)

Guidance literature:

With cadmium(II) chloride;

DOI:10.1021/jo01102a015

Reference yield:

1-bromo-3-chlorobenzene (108-37-2) + 2-bromobenzoic acid chloride (7154-66-7) → 2-bromo-3'-chlorobenzophenone (99586-30-8)

Guidance literature:

Yield given. Multistep reaction; 2.) toluene, reflux, 1 h;

DOI:10.1016/S0957-4166(00)82179-5

Reference yield: 92.0%

2-bromo-3'-chlorobenzophenone (99586-30-8) → (R)-(2-Bromo-phenyl)-(3-chloro-phenyl)-methanol (105904-28-7,143880-84-6)

Guidance literature:

With lithium aluminium tetrahydride; (R)-(-)-2-(2-iso-indolinyl)butan-1-ol; In diethyl ether; for 0.25h;

DOI:10.1016/S0957-4166(00)82179-5

upstream raw materials:

2-bromobenzoic acid chloride

(3-chlorophenyl)magnesium bromide

1-bromo-3-chlorobenzene

Downstream raw materials:

1-bromo-2-(3-chlorobenzyl)benzene

(2-bromophenyl)(3-chlorophenyl)methanol

(R)-(2-Bromo-phenyl)-(3-chloro-phenyl)-methanol

Refernces