2,3-Dihydro-5-methylfuran

Base Information

• Chemical Name: 2,3-Dihydro-5-methylfuran
• CAS No.: 1487-15-6
• Molecular Formula: C5H8 O
• Molecular Weight: 84.1179
• Hs Code.: 2932190090
• European Community (EC) Number: 216-067-6
• UNII: Y543M5WR3R
• DSSTox Substance ID: DTXSID10164066
• Nikkaji Number: J120.984A
• Wikidata: Q27122708
• Metabolomics Workbench ID: 57835
• Mol file: 1487-15-6.mol

Synonyms:1487-15-6;2,3-Dihydro-5-methylfuran;5-Methyl-2,3-dihydrofuran;4,5-DIHYDRO-2-METHYLFURAN;Furan, 2,3-dihydro-5-methyl-;4,5-Dihydrosylvan;2-Methyl-4,5-dihydrofuran;EINECS 216-067-6;Y543M5WR3R;UNII-Y543M5WR3R;4,5-Dihydro-2-methyl furan;CHEBI:51677;DTXSID10164066;2,3-Dihydro-5-methylfuran 97%;2,3-Dihydro-5-methylfuran, 97%;AKOS015912436;AB00300;CS-0446985;FT-0633603;J-008508;Q27122708

Chemical Property of 2,3-Dihydro-5-methylfuran

Chemical Property:

• Vapor Pressure: 46mmHg at 25°C
• Refractive Index: n20/D 1.432(lit.)
• Boiling Point: 98.4°Cat760mmHg
• Flash Point: °C
• PSA: 9.23000
• Density: 0.924g/cm³
• LogP: 1.31050
• Storage Temp.: 2-8°C
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 84.057514874
• Heavy Atom Count: 6
• Complexity: 74

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,3-Dihydro-5-methylfuran 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F
• Statements: 11
• Safety Statements: 16-29-33

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=CCCO1

Technology Process of 2,3-Dihydro-5-methylfuran

There total 38 articles about 2,3-Dihydro-5-methylfuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

5-Hydroxy-2-pentanone (1071-73-4) → 2-Methyl-4,5-dihydrofuran (1487-15-6)

Guidance literature:

With phosphoric acid; at 200 ℃; Concentration;

Reference yield: 88.0%

Echavarren's catalyst (866641-66-9) + pent-3-yn-1-ol (10229-10-4) → 2-Methyl-4,5-dihydrofuran (1487-15-6) + C45H61Au2OP2(1+)*F6Sb(1-)

Guidance literature:

With N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; In chloroform-d1; at 20 ℃; for 0.1h;

DOI:10.1002/chem.201204491

Reference yield: 80.0%

[Ph3P-Au-(NCCH3)](1+)*SbF6(1-) (883995-03-7) + pent-3-yn-1-ol (10229-10-4) → 2-Methyl-4,5-dihydrofuran (1487-15-6) + C41H37Au2OP2(1+)*F6Sb(1-)

Guidance literature:

With N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; In chloroform-d1; at 20 ℃; for 0.1h;

DOI:10.1002/chem.201204491

upstream raw materials:

tetrahydrofurfuryl bromide

2-methyleneoxolane

pent-1-yn-5-ol

5-Hydroxy-2-pentanone

Downstream raw materials:

2,2-dimethyltetrahydrofuran

2-methyl-2-phenyltetrahydrofuran

3-penten-2-one

Cyclopropyl methyl ketone

Refernces

• 1、 Martin, Pilar,Tuazon, Ernesto C.,Aschmann, Sara M.,Arey, Janet,Atkinson, Roger. "Formation and atmospheric reactions of 4,5-dihydro-2-methylfuran". . p. 11492 - 11501. Retrieved 2002.
• 2、 Oakes, Fred T.,Sebastian, John F.. "Direct Observation of Acyl Anion Equivalents by Carbon-13 Fourier Transform Nuclear Magnetic Resonance". . p. 4959 - 4961. Retrieved 1980.
• 3、 -. "Preparation method of 4-(BOC-amino)-1-butanol". Paragraph 0051-0052; 0058-0059; 0065-0066. . Retrieved 2021/01/28.
• 4、 -. "Preparation method and application of 2-methyl tetrahydrofuran-3-thiol". Paragraph 0018; 0040-0045. . Retrieved 2018/09/12.