3-nitro-4-propoxy-, 2-(diethylamino)ethyl ester Benzoic acid

Base Information

• Chemical Name: 3-nitro-4-propoxy-, 2-(diethylamino)ethyl ester Benzoic acid
• CAS No.: 736870-51-2
• Molecular Formula: C16H24N2O5
• Molecular Weight: 324.377
• Mol file: 736870-51-2.mol

Synonyms:3-NITRO-4-PROPOXY-,2-(DIETHYLAMINO)ETHYL ESTER BENZOIC ACID;3-NITRO-4-PROPOXY-,2-(DIETHYLAMINO)ETHYLESTERBENZOICACID;3-nitro-4-propoxy-, 2-(diethylamino)ethyl ester Benzoic acid;

Chemical Property of 3-nitro-4-propoxy-, 2-(diethylamino)ethyl ester Benzoic acid

Chemical Property:

• PSA: 84.59000
• Density: 1.134
• LogP: 3.40540

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-nitro-4-propoxy-, 2-(diethylamino)ethyl ester Benzoic acid

There total 3 articles about 3-nitro-4-propoxy-, 2-(diethylamino)ethyl ester Benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-nitro-4-hydroxybenzoic acid (616-82-0) → 3-nitro-4-propoxy-benzoic acid-(2-diethylamino-ethyl ester) (736870-51-2)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃; xylene / Erwaermen des Reaktionsprodukts mit wss.-aethanol. NaOH

2: isopropyl alcohol

With potassium carbonate; isopropyl alcohol; xylene;

DOI:10.1021/ja01123a005

Reference yield:

3-nitro-4-propoxybenzoic acid (35288-44-9) + 2-(diethylamino)ethyl chloride (100-35-6) → 3-nitro-4-propoxy-benzoic acid-(2-diethylamino-ethyl ester) (736870-51-2)

Guidance literature:

With isopropyl alcohol;

DOI:10.1021/ja01123a005

Reference yield:

→ 3-nitro-4-propoxy-benzoic acid-(2-diethylamino-ethyl ester) (736870-51-2)

Guidance literature:

Saeure (V), Diethylaminoethanol;

upstream raw materials:

3-nitro-4-propoxybenzoic acid

2-(diethylamino)ethyl chloride

3-nitro-4-hydroxybenzoic acid

Downstream raw materials:

Proparacain

Refernces