4-(METHYLSULFINYL)-1-BUTYLAMINE

Base Information

• Chemical Name: 4-(METHYLSULFINYL)-1-BUTYLAMINE
• CAS No.: 908337-04-2
• Molecular Formula: C₆H₁₅NOS
• Molecular Weight: 149.257
• Mol file: 908337-04-2.mol

Synonyms:4-(METHYLSULFINYL)-1-BUTYLAMINE;

Chemical Property of 4-(METHYLSULFINYL)-1-BUTYLAMINE

Chemical Property:

• PSA: 62.30000
• LogP: 2.05990
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility.: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

4-(Methylsulfinyl)-1-butylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(METHYLSULFINYL)-1-BUTYLAMINE

There total 2 articles about 4-(METHYLSULFINYL)-1-BUTYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

5-methylthiopentylamine (55021-78-8) → 5-methylsulfinylpentylamine (908337-04-2)

Guidance literature:

With sulfuric acid; dihydrogen peroxide; In methanol; water; isopropyl alcohol; at 20 ℃; for 3h;

DOI:10.1021/jf1003573

Reference yield:

5-bromopentan-1-nitrile (5414-21-1) → 5-methylsulfinylpentylamine (908337-04-2)

Guidance literature:

Multi-step reaction with 3 steps

1: methanol / 7 h / Reflux

2: lithium aluminium tetrahydride / diethyl ether / 0.5 h / Reflux

3: sulfuric acid; dihydrogen peroxide / methanol; water; isopropyl alcohol / 3 h / 20 °C

With lithium aluminium tetrahydride; sulfuric acid; dihydrogen peroxide; In methanol; diethyl ether; water; isopropyl alcohol;

DOI:10.1021/jf1003573

Reference yield: 64.0%

thiophosgene (463-71-8) + 5-methylsulfinylpentylamine (908337-04-2) → alyssin (646-23-1)

Guidance literature:

With sodium hydroxide; In chloroform; at 20 ℃; for 1h;

DOI:10.1021/jf1003573

upstream raw materials:

5-methylthiopentylamine

5-bromopentan-1-nitrile

Downstream raw materials:

alyssin

(R)-1-isothiocyanato-5-(methylsulfinyl)pentane

Refernces