9b-(4-chlorophenyl)-1,2,3,9b-tetrahydro-1-[4-Methylphenyl)sulfonyl]-5H-iMidazo[2,1-α]isoindol-5-one

Base Information

• Chemical Name: 9b-(4-chlorophenyl)-1,2,3,9b-tetrahydro-1-[4-Methylphenyl)sulfonyl]-5H-iMidazo[2,1-α]isoindol-5-one
• CAS No.: 22590-16-5
• Molecular Formula: C23H19ClN2O3S
• Molecular Weight: 438.934
• Mol file: 22590-16-5.mol

Synonyms:9b-(4-chloro-phenyl)-1-(toluene-4-sulfonyl)-1,2,3,9b-tetrahydro-imidazo[2,1-a]isoindol-5-one;9b-(4-chlorophenyl)-1,2,3,9b-tetrahydro-1-[4-Methylphenyl)sulfonyl]-5H-iMidazo[2,1-α]isoindol-5-one;5H-IMidazo[2,1-a]isoindol-5-one, 9b-(4-chlorophenyl)-1,2,3,9b-tetrahydro-1-[(4-Methylphenyl)sulfonyl]-

Chemical Property of 9b-(4-chlorophenyl)-1,2,3,9b-tetrahydro-1-[4-Methylphenyl)sulfonyl]-5H-iMidazo[2,1-α]isoindol-5-one

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Use Description: 9b-(4-chlorophenyl)-1,2,3,9b-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-imidazo[2,1-α]isoindol-5-one is a chemical compound with potential applications in various fields. In the field of medicinal chemistry and pharmaceuticals, it can serve as a valuable intermediate for the synthesis of novel compounds with potential pharmacological properties. Its role is pivotal in the structural modification of molecules, enabling the creation of compounds that can target specific biological pathways or receptors, potentially leading to the development of new medications. Additionally, in academic research and organic chemistry, this compound can be employed as a building block for the synthesis of complex organic molecules, aiding in the study of chemical reactions and the development of new chemical methodologies. Its versatility across these fields underscores its significance in drug discovery, chemical research, and the potential advancement of treatments for various medical conditions, ultimately contributing to healthcare and scientific knowledge.

Technology Process of 9b-(4-chlorophenyl)-1,2,3,9b-tetrahydro-1-[4-Methylphenyl)sulfonyl]-5H-iMidazo[2,1-α]isoindol-5-one

There total 2 articles about 9b-(4-chlorophenyl)-1,2,3,9b-tetrahydro-1-[4-Methylphenyl)sulfonyl]-5H-iMidazo[2,1-α]isoindol-5-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-toluenesulfonyl chloride (98-59-9) + 9b-(p-chlorophenyl)-1,2,3,9b-tetrahydro-1H-imidazo[2,1-a]isoindol-5-one (6038-49-9) → 9b-(4-chloro-phenyl)-1-(toluene-4-sulfonyl)-1,2,3,9b-tetrahydro-imidazo[2,1-a]isoindol-5-one (22590-16-5)

Guidance literature:

With pyridine;

Reference yield:

→ 9b-(4-chloro-phenyl)-1-(toluene-4-sulfonyl)-1,2,3,9b-tetrahydro-imidazo[2,1-a]isoindol-5-one (22590-16-5)

Guidance literature:

entspr. Benzoylbenzoesaeure, N-Tosyl-ethylendiamin;

Reference yield:

sulfate salt of 4'-chloro-2-(2-imidazolin-2-yl)benzophenone + 9b-(4-chloro-phenyl)-1-(toluene-4-sulfonyl)-1,2,3,9b-tetrahydro-imidazo[2,1-a]isoindol-5-one (22590-16-5) → Mazindol (22232-71-9)

Guidance literature:

In sulfuric acid;

upstream raw materials:

p-toluenesulfonyl chloride

9b-(p-chlorophenyl)-1,2,3,9b-tetrahydro-1H-imidazo[2,1-a]isoindol-5-one

Downstream raw materials:

Mazindol

Refernces

• 1、 -. "Imidazolinyl phenyl carbonyl compounds acid addition salts and related compounds". . . Retrieved 2008/06/13.