2-Mercapto-N'-(2-Mercaptoacetyl)-N,N'-diMethylacetohydrazide

Base Information

• Chemical Name: 2-Mercapto-N'-(2-Mercaptoacetyl)-N,N'-diMethylacetohydrazide
• CAS No.: 131760-67-3
• Molecular Formula: C6H12N2O2S2
• Molecular Weight: 208.305
• Mol file: 131760-67-3.mol

Synonyms:2-Mercapto-N'-(2-Mercaptoacetyl)-N,N'-diMethylacetohydrazide

Chemical Property of 2-Mercapto-N'-(2-Mercaptoacetyl)-N,N'-diMethylacetohydrazide

Chemical Property:

• PSA: 118.22000
• LogP: -0.32220

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N,N''-Dimethyl-N,N''-bis(mercaptoacetyl)hydrazine can be used in products to permanently wave hair. It can also be used to oxidize and prepare agents for use for illuminated analytical reactions and as a dye-labeled compound.

Technology Process of 2-Mercapto-N'-(2-Mercaptoacetyl)-N,N'-diMethylacetohydrazide

There total 4 articles about 2-Mercapto-N'-(2-Mercaptoacetyl)-N,N'-diMethylacetohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,4-dithio-D,L-threitol (27565-41-9) + 1,2-dimethyl-3,8-dioxo-1,2,5,6-diazadithiocane (131760-68-4) → trans-1,2-dithiane-4,5-diol (16096-98-3,37031-12-2,40227-25-6,74185-01-6,86023-22-5,89825-28-5,14193-38-5) + N,N'-dimethyl-N,N'-bis(mercaptoacetyl)hydrazine (131760-67-3)

Guidance literature:

With buffer (pH 7, 50 mM phosphate); Equilibrium constant;

DOI:10.1021/jo00007a018

Reference yield:

1,6-dimercaptohexane (1191-43-1) + 1,2-dimethyl-3,8-dioxo-1,2,5,6-diazadithiocane (131760-68-4) → 1,2-dithiacyclooctane (6008-69-1) + N,N'-dimethyl-N,N'-bis(mercaptoacetyl)hydrazine (131760-67-3)

Guidance literature:

With buffer (pH 7, 50 mM phosphate); Equilibrium constant;

DOI:10.1021/jo00007a018

Reference yield:

dihydrolipoic acid (462-20-4) + 1,2-dimethyl-3,8-dioxo-1,2,5,6-diazadithiocane (131760-68-4) → N,N'-dimethyl-N,N'-bis(mercaptoacetyl)hydrazine (131760-67-3) + Thioctic acid (1077-28-7,62-46-4)

Guidance literature:

With buffer (pH 7.0, 2 mM EDTA, 0.1 M phosphate); Equilibrium constant;

DOI:10.1021/jo00007a018

upstream raw materials:

1,4-dithio-D,L-threitol

1,2-dimethyl-3,8-dioxo-1,2,5,6-diazadithiocane

1,6-dimercaptohexane

dihydrolipoic acid

Downstream raw materials:

1,4-dithio-D,L-threitol

1,2-dimethyl-3,8-dioxo-1,2,5,6-diazadithiocane

dihydrolipoic acid

1,6-dimercaptohexane

Refernces

• 1、 Lees, Watson J.,Singh, Rajeeva,Whitesides, George M.. "meso-2,5-Dimercapto-N,N,N',N'-tetramethyladipamide: A Readily Available, Kinetically Rapid Reagent for the Reduction of Disulfides in Aqueous Solution". . p. 7328 - 7331. Retrieved 2007/10/02.