3,6-Dichloropicolinonitrile

Base Information

• Chemical Name: 3,6-Dichloropicolinonitrile
• CAS No.: 1702-18-7
• Molecular Formula: C6H2Cl2N2
• Molecular Weight: 173.001
• Hs Code.: 2933399090
• European Community (EC) Number: 873-245-1
• DSSTox Substance ID: DTXSID40352535
• Wikidata: Q82129732
• Mol file: 1702-18-7.mol

Synonyms:3,6-Dichloropicolinonitrile;1702-18-7;3,6-dichloropyridine-2-carbonitrile;2-CYANO-3,6-DICHLOROPYRIDINE;3,6-DICHLORO-2-PYRIDINECARBONITRILE;3,6-Dichloro-pyridine-2-carbonitrile;MFCD00546824;2-Pyridinecarbonitrile, 3,6-dichloro-;3,6-dichloro-2-cyanopyridine;SCHEMBL7108696;DTXSID40352535;AFSVHZPQZBOZDK-UHFFFAOYSA-N;HMS1786B16;BAA70218;STK965392;AKOS001043256;AB06438;AM807226;AS-19701;CS-0059239;FT-0681879;EN300-57209;A26069;F30110;J-511399;Z56868958;F3097-0586

Chemical Property of 3,6-Dichloropicolinonitrile

Chemical Property:

• PSA: 36.68000
• LogP: 2.26008
• Storage Temp.: Inert atmosphere,Room Temperature
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 171.9595035
• Heavy Atom Count: 10
• Complexity: 162

Purity/Quality:

98%,99%, ^*data from raw suppliers

3,6-dichloropicolinonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=NC(=C1Cl)C#N)Cl

Technology Process of 3,6-Dichloropicolinonitrile

There total 7 articles about 3,6-Dichloropicolinonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.5%

2-cyano-3,6-dichloropyridine-1-oxide → 3,6-dichloro-2-pyridinecarbonitrile (1702-18-7)

Guidance literature:

With trichlorophosphate; at 75 ℃;

Reference yield: 53.6%

2,5-dichloro-1-oxido-pyridin-1-ium (53976-62-8) → 3,6-dichloro-2-pyridinecarbonitrile (1702-18-7)

Guidance literature:

With dimethyl sulfate; In water;

Reference yield: 52.2%

6-chloro-pyridine-2-carbonitrile (33252-29-8) → 5,6-dichloropyridine-2-carbonitrile (185107-64-6) + 3,6-dichloro-2-pyridinecarbonitrile (1702-18-7)

Guidance literature:

With iron(III) chloride; chlorine; at 150 - 155 ℃; for 20h; under 760.051 Torr; Temperature; Reagent/catalyst;

upstream raw materials:

2,5-dichloro-1-oxido-pyridin-1-ium

2-fluoro-3,6-dichloropyridine

2,3,6-trichloropyridine

6-chloro-pyridine-2-carbonitrile

Downstream raw materials:

Clopyralid

3-fluoro-6-phenyl-2-pyridinecarbonitrile

3-chloro-6-phenyl-2-pyridinecarbonitrile

Refernces

• 1、 -. "Preparation method of 3,6-dichloro-2-pyridinecarboxylic acid". . . Retrieved 2017/08/25.
• 2、 -. "6-(Nonsubstituted or substituted) phenoxy picolinic acids, process of preparing the same, and agricultural/horticultural germicides containing the same". . . Retrieved 2008/06/13.