2,3,6-Trichloropyridine

Base Information

• Chemical Name: 2,3,6-Trichloropyridine
• CAS No.: 6515-09-9
• Molecular Formula: C5H2 Cl3 N
• Molecular Weight: 182.437
• Hs Code.: 2933399090
• European Community (EC) Number: 692-144-1,835-803-2
• DSSTox Substance ID: DTXSID0073374
• Nikkaji Number: J51.347D
• Wikidata: Q82001778
• Mol file: 6515-09-9.mol

Synonyms:2,3,6-TRICHLOROPYRIDINE;6515-09-9;29154-14-1;Pyridine, 2,3,6-trichloro-;MFCD00463516;BRN 0118592;2,5,6-Trichloropyridine;3-Azido-2,3-dideoxyuridine;2,6-Dichloro-3-chloropyridine;SCHEMBL3363278;SCHEMBL9362573;DTXSID0073374;AMY12438;AC-960;AKOS005258298;CS-W021481;GS-6541;SB52369;SY023494;LS-132113;A5467;A8854;FT-0600050;T3428;EN300-61260;J-506894

Chemical Property of 2,3,6-Trichloropyridine

Chemical Property:

• Vapor Pressure: 0.134mmHg at 25°C
• Melting Point: 66-67 °C
• Refractive Index: 1.6300 (estimate)
• Boiling Point: 224.691°C at 760 mmHg
• PKA: -3.79±0.10(Predicted)
• Flash Point: 111.159°C
• PSA: 12.89000
• Density: 1.539g/cm³
• LogP: 3.04180
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility.: soluble in Methanol
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 180.925282
• Heavy Atom Count: 9
• Complexity: 98.2

Purity/Quality:

99% ^*data from raw suppliers

2,3,6-Trichloropyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=NC(=C1Cl)Cl)Cl

Technology Process of 2,3,6-Trichloropyridine

There total 3 articles about 2,3,6-Trichloropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 1.0%

2,3,4,5,6-pentachloropyridine (2176-62-7) → 2,3,6-trichloropyridine (6515-09-9) + 2,3,5-trichloropyridine (16063-70-0) + 2,3,5,6-tetrachloropyridine (2402-79-1)

Guidance literature:

With ammonium chloride; dimethyl methane phosphonate; zinc; In water; at 85 - 90 ℃; Product distribution; other ammonium salts; other methylphosphonates/phosphates;

Reference yield:

3-Methylpyridine (108-99-6) → 2,3,6-trichloropyridine (6515-09-9) + 2-chloro-5-(Trichloromethyl)-pyridine (69045-78-9) + 2,3-dichloro-5-(trichloromethyl)pyridine (69045-83-6)

Guidance literature:

With chlorine; In tetrachloromethane; at 400 ℃; for 4h;

Reference yield:

pyridin-3-ylamine (462-08-8) → 2,3-dichloro-pyridine (2402-77-9) + 2,3,6-trichloropyridine (6515-09-9)

Guidance literature:

With hydrogenchloride; dihydrogen peroxide; iron(II) chloride; In water; at 25 - 30 ℃; for 0.333333h;

upstream raw materials:

2,3,4,5,6-pentachloropyridine

3-Methylpyridine

pyridin-3-ylamine

Downstream raw materials:

3-chloro-2,6-difluoropyridine

5-bromo-2-(3-chloro-pyridin-2-yl)-3,4-dihydro-2H-pyrazole-3-carboxylic acid ethyl ester

rynaxypyr

(3-chloro-2-pyridyl)hydrazine

Refernces

• 1、 -. "Method for preparing 2, 3, 6-trichloropyridine". Paragraph 0054; 0055. . Retrieved 2019/05/22.