1-Indanamine

Base Information

• Chemical Name: 1-Indanamine
• CAS No.: 34698-41-4
• Molecular Formula: C9H11N
• Molecular Weight: 133.193
• Hs Code.: 29214980
• European Community (EC) Number: 252-158-7
• NSC Number: 62540
• UNII: 8UP8M3CGS8
• DSSTox Substance ID: DTXSID20902754
• Nikkaji Number: J88.962H
• Wikidata: Q72438213
• ChEMBL ID: CHEMBL158574
• Mol file: 34698-41-4.mol

Synonyms:1-Indanamine(6CI,7CI);(RS)-1-Aminoindan;1-Indanylamine;2,3-Dihydro-1H-inden-1-amine;2,3-Dihydro-1H-inden-1-ylamine;NSC 62540;TVP136;dl-Indan-1-amine;1H-Inden-1-amine,2,3-dihydro-;

Chemical Property of 1-Indanamine

Chemical Property:

• Appearance/Colour: Clear liquid
• Vapor Pressure: 0.0886mmHg at 25°C
• Melting Point: 15 °C(lit.)
• Refractive Index: n20/D 1.562
• Boiling Point: 225 °C at 760 mmHg
• PKA: 9.21(at 22℃)
• Flash Point: 94.4 °C
• PSA: 26.02000
• Density: 1.056 g/cm³
• LogP: 2.33290
• Storage Temp.: Refrigerator (+4°C)
• Sensitive.: Air Sensitive
• Solubility.: insoluble
• Water Solubility.: insoluble
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 133.089149355
• Heavy Atom Count: 10
• Complexity: 122

Purity/Quality:

99% ^*data from raw suppliers

1-Aminoindan ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-37/39-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1CC2=CC=CC=C2C1N

Technology Process of 1-Indanamine

There total 84 articles about 1-Indanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

indan-1-one oxime (68253-35-0,100485-57-2,3349-60-8) → 2,3-dihydro-1H-inden-1-amine (34698-41-4)

Guidance literature:

With ammonia; hydrogen; In methanol; at 42 ℃; for 20h; under 2625.26 Torr;

Reference yield: 94.0%

(S)-1-Aminoindane (10277-74-4,34698-41-4,61341-86-4,61949-83-5) → 2,3-dihydro-1H-inden-1-amine (34698-41-4)

Guidance literature:

potassium tert-butylate; In dimethyl sulfoxide; at 120 ℃; for 2h; Inert atmosphere;

Reference yield: 90.0%

inden-1-one (83-33-0) → 2,3-dihydro-1H-inden-1-amine (34698-41-4)

Guidance literature:

With 4-methoxy-N-(1-(naphthalen-2-yl)ethylidene)aniline; ammonium formate; In methanol; at 80 ℃; for 12h; chemoselective reaction; Inert atmosphere;

DOI:10.1002/chem.201303541

upstream raw materials:

1-chloroindane

3,4-dimercaptotoluene

1-isothiocyanatoindane

indan-1-one oxime

Downstream raw materials:

N-(2,3-dihydro-1H-inden-1-yl)acetamide

(S)-1-Aminoindane

(R)-1-Aminoindane

C₁₆H₁₅NO

Refernces

• 1、 Ford jun.. "". . p. 815. Retrieved 1968.
• 2、 Dai, Zengjin,Pan, Ying-Min,Wang, Shou-Guo,Yin, Qin,Zhang, Xumu. "Direct reductive amination of ketones with ammonium salt catalysed by Cp*Ir(iii) complexes bearing an amidato ligand". supporting information. p. 8934 - 8939. Retrieved 2021/11/04.
• 3、 Ding, Du,Jiang, Hua-Jie,Wang, Tao,Wu, Xiang,Zhang, Ying,Zhao, Li-Ping. "Enantioselective synthesis of 1-aminoindene derivativesviaasymmetric Br?nsted acid catalysis". supporting information. p. 9680 - 9683. Retrieved 2021/09/30.