Acetic acid, anhydride with hypoiodous acid

Base Information

• Chemical Name: Acetic acid, anhydride with hypoiodous acid
• CAS No.: 6540-76-7
• Molecular Formula: C6H9IO6
• Molecular Weight: 185.949
• DSSTox Substance ID: DTXSID00215713
• Mol file: 6540-76-7.mol

Synonyms:Iodine monoacetate;Acetic acid, anhydride with hypoiodous acid;6540-76-7;DTXSID00215713

Chemical Property of Acetic acid, anhydride with hypoiodous acid

Chemical Property:

• Vapor Pressure: 5.94mmHg at 25°C
• Boiling Point: 141.1°Cat760mmHg
• Flash Point: 54.4°C
• Density: g/cm³
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 245.93891
• Heavy Atom Count: 9
• Complexity: 85.1

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)OC(=O)C.OI

Technology Process of Acetic acid, anhydride with hypoiodous acid

There total 8 articles about Acetic acid, anhydride with hypoiodous acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[bis(acetoxy)iodo]benzene (3240-34-4) → iodobenzene (591-50-4) + iodine monoacetate (6540-76-7)

Guidance literature:

With iodine; In [D₃]acetonitrile;

DOI:10.1039/c6ob00532b

Reference yield:

acetic anhydride (108-24-7) → iodine monoacetate (6540-76-7)

Guidance literature:

With iodine;

Reference yield:

acetic anhydride (108-24-7) + acetic acid (64-19-7,77671-22-8) → iodine monoacetate (6540-76-7)

Guidance literature:

With Oxone; iodine; at 50 ℃; for 21h; Green chemistry;

DOI:10.1055/s-0036-1589119

upstream raw materials:

acetic anhydride

sodium acetate

iodine

silver(I) acetate

Downstream raw materials:

2-iodo-1-phenylethyl acetate

2-iodo-1-(3-nitrophenyl)ethan-1-ol

1-iodo-2-phenylpropan-2-yl acetate

Refernces

• 1、 Zaytsev, Vladimir P.,Mertsalov, Dmitriy F.,Trunova, Anastasiya M.,Khanova, Anastasiya V.,Nikitina, Eugeniya V.,Sinelshchikova, Anna А.,Grigoriev, Mikhail S.. "Iodine Acetate as a Mild Selective Agent for the Wagner–Meerwein Rearrangement in 3a,6-Epoxyisoindoles". . p. 930 - 935. Retrieved 2020.
• 2、 Brown, Caleb A.,Guzmán Santiago, Alexis J.,Ison, Elon A.,Sommer, Roger D.. "Identification of key functionalization species in the Cp?Ir(iii)-catalyzed-: ortho halogenation of benzamides". supporting information. p. 16166 - 16174. Retrieved 2020/12/03.