(9-phenyl-9H-carbazol-2-yl)boronic acid

Base Information

• Chemical Name: (9-phenyl-9H-carbazol-2-yl)boronic acid
• CAS No.: 1001911-63-2
• Molecular Formula: C18 H14 BNO2
• Molecular Weight: 287.126
• Hs Code.: 2933990090
• Mol file: 1001911-63-2.mol

Synonyms:(9-phenyl-9H-carbazol-2-yl)boronic acid;(9-phenyl-9H-carbazol-2-yl)boronic acid (2PCBA);9-Phenylcarbazole-2-boronic acid;B-(9-Phenyl-9H-carbazol-2-yl)-boronic acid;2-BAPC

Chemical Property of (9-phenyl-9H-carbazol-2-yl)boronic acid

Chemical Property:

• Boiling Point: 466.0±51.0 °C(Predicted)
• PKA: 8.91±0.30(Predicted)
• PSA: 45.39000
• Density: 1.20±0.1 g/cm3(Predicted)
• LogP: 2.46350
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility.: very slightly in Tetrahydrofuran

Purity/Quality:

99% ^*data from raw suppliers

(9-Phenyl-9H-carbazol-2-yl)boronicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (9-phenyl-9H-carbazol-2-yl)boronic acid can be used as an intermediate in organic synthesis, mainly used in laboratory research and development and in the process of chemical and pharmaceutical synthesis.

Technology Process of (9-phenyl-9H-carbazol-2-yl)boronic acid

There total 18 articles about (9-phenyl-9H-carbazol-2-yl)boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

Triisopropyl borate (5419-55-6) + 9-(phenyl)-2-bromo-9H-carbazole (94994-62-4) → (9‐phenyl‐9H‐carbazol‐2‐yl)boronic acid (1001911-63-2)

Guidance literature:

9-(phenyl)-2-bromo-9H-carbazole; With n-butyllithium; In tetrahydrofuran; at -75 - 0 ℃; for 1h; Inert atmosphere;

Triisopropyl borate; In tetrahydrofuran; at -70 - 20 ℃; for 12h; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; water; for 0.5h; Temperature; Inert atmosphere;

Reference yield: 81.0%

Trimethyl borate (121-43-7,63156-11-6) + 9-(phenyl)-2-bromo-9H-carbazole (94994-62-4) + water (7732-18-5) → (9‐phenyl‐9H‐carbazol‐2‐yl)boronic acid (1001911-63-2)

Guidance literature:

9-(phenyl)-2-bromo-9H-carbazole; With n-butyllithium; In tetrahydrofuran; at -78 - 0 ℃; for 1h;

Trimethyl borate; In tetrahydrofuran; at -78 - 20 ℃; for 12h;

water; With hydrogenchloride; In tetrahydrofuran;

Reference yield: 79.0%

Trimethyl borate (121-43-7,63156-11-6) + 9-(phenyl)-2-bromo-9H-carbazole (94994-62-4) → (9‐phenyl‐9H‐carbazol‐2‐yl)boronic acid (1001911-63-2)

Guidance literature:

9-(phenyl)-2-bromo-9H-carbazole; With n-butyllithium; In tetrahydrofuran; at -78 - 0 ℃; for 1h; Inert atmosphere;

Trimethyl borate; In tetrahydrofuran; at -78 - 20 ℃; for 12h;

upstream raw materials:

4-Bromophenylboronic acid

4'-bromo-2-nitrobiphenyl

2-bromo-9H-carbazole

o-nitroiodobenzene

Downstream raw materials:

2-(2-nitrophenyl)-9-phenyl-9H-carbazole

5-phenyl-5,11-dihydro-indolo[3,2-b]carbazole

C₃₀H₁₉BrN₂

C₃₀H₂₁BN₂O₂

Refernces

• 1、 -. "Organic compound, and organic electroluminescent device and electronic device using the same". Paragraph 0138-0140; 0141; 0145. . Retrieved 2021/11/10.
• 2、 -. "Organic high molecular compound and application thereof". Paragraph 0211-0214. . Retrieved 2018/03/26.