Benzoyl-furoyl

Base Information

• Chemical Name: Benzoyl-furoyl
• CAS No.: 86358-28-3
• Molecular Formula: C12H8O3
• Molecular Weight: 200.194
• NSC Number: 121396
• DSSTox Substance ID: DTXSID20298200
• Nikkaji Number: J82.021K
• Wikidata: Q82039858
• Mol file: 86358-28-3.mol

Synonyms:Benzoyl-furoyl;86358-28-3;1-(furan-2-yl)-2-phenylethane-1,2-dione;NSC121396;SCHEMBL15665397;DTXSID20298200;NSC-121396

Chemical Property of Benzoyl-furoyl

Chemical Property:

• Vapor Pressure: 0.000232mmHg at 25°C
• Boiling Point: 325.3°Cat760mmHg
• Flash Point: 150.8°C
• Density: 1.226g/cm³
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 200.047344113
• Heavy Atom Count: 15
• Complexity: 254

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)C(=O)C2=CC=CO2

Technology Process of Benzoyl-furoyl

There total 20 articles about Benzoyl-furoyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-(2-phenylethynyl)furan (35133-77-8) → 1-(furan-2-yl)-2-phenyl-ethane-1,2-dione (86358-28-3)

Guidance literature:

With [bis(trifluoromethanesulfonyl)imidate](triphenylphosphine)gold(I); 2,3-dichloropyridine N-oxide; at 60 ℃; for 6h;

DOI:10.1021/acs.joc.9b02785

Reference yield: 96.0%

2-(Furan-2-yl)-2-hydroxy-1-phenylethanone (86352-16-1) → 1-(furan-2-yl)-2-phenyl-ethane-1,2-dione (86358-28-3)

Guidance literature:

With 2,6-dimethylpyridine; 2,3-dibromo-3-phenyl-propionic acid ethyl ester; triphenylantimony dibromide; In chloroform-d1; at 70 ℃; for 72h;

DOI:10.1246/cl.1985.1577

Reference yield: 94.0%

1-(furan-2-yl)-2-hydroxy-2-phenylethanone (36715-43-2) → 1-(furan-2-yl)-2-phenyl-ethane-1,2-dione (86358-28-3)

Guidance literature:

With triphenylantimony dibromide; 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; for 18h; Ambient temperature;

DOI:10.1246/cl.1985.1577

upstream raw materials:

2-(Furan-2-yl)-2-hydroxy-1-phenylethanone

1-(furan-2-yl)-2-hydroxy-2-phenylethanone

furfural

N-phenyl-benzimidoyl chloride

Downstream raw materials:

2-(furan-2-yl)-3-phenylquinoxaline-6-carboxylic acid

nitrostyrene

benzoic acid ethyl ester

5-furan-2-yl-5-phenyl-imidazolidine-2,4-dione

Refernces

• 1、 Zhai, Yadong,Su, Zhenni,Jiang, Hao,Rong, Jing,Qiu, Xianfan,Tao, Chuanzhou. "B2pin2-mediated copper-catalyzed oxidation of alkynes into 1,2-diketones using molecular oxygen". supporting information. p. 843 - 846. Retrieved 2019/02/19.
• 2、 Zhou, Peng-Jun,Li, Cheng-Kun,Zhou, Shao-Fang,Shoberu, Adedamola,Zou, Jian-Ping. "Copper-catalyzed TEMPO oxidative cleavage of 1,3-diketones and β-keto esters for the synthesis of 1,2-diketones and α-keto esters". . p. 2629 - 2637. Retrieved 2017/04/03.