1-Benzyl-5-iodoiMidazole

Base Information

• Chemical Name: 1-Benzyl-5-iodoiMidazole
• CAS No.: 941286-76-6
• Molecular Formula: C10H9IN2
• Molecular Weight: 284.09633
• Mol file: 941286-76-6.mol

Synonyms:1-Benzyl-5-iodoiMidazole;1-benzyl-5-iodo-1H-imidazole

Chemical Property of 1-Benzyl-5-iodoiMidazole

Chemical Property:

• PSA: 17.82000
• LogP: 2.53600

Purity/Quality:

99% ^*data from raw suppliers

1-Benzyl-5-iodoimidazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Benzyl-5-iodoiMidazole

There total 3 articles about 1-Benzyl-5-iodoiMidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

4-iodoimidazole (71759-89-2) + benzyl chloride (100-44-7) → 1-benzyl-5-iodo-1H-imidazole (941286-76-6) + 1-benzyl-4-iodo-1H-imidazole (536760-32-4)

Guidance literature:

With sodium hydroxide; In water; N,N-dimethyl-formamide; at 30 - 40 ℃; for 1h;

DOI:10.1021/jo0626008

Reference yield: 60.0%

benzyl chloride (100-44-7) + 4(5)-iodoimidazole → 1-benzyl-5-iodo-1H-imidazole (941286-76-6) + 1-benzyl-4-iodo-1H-imidazole (536760-32-4)

Guidance literature:

With sodium hydroxide; In water; dimethyl sulfoxide;

DOI:10.3987/com-02-9598

Reference yield:

4-iodoimidazole (71759-89-2) + benzyl bromide (100-39-0) → 1-benzyl-5-iodo-1H-imidazole (941286-76-6) + 1-benzyl-4-iodo-1H-imidazole (536760-32-4)

Guidance literature:

4-iodoimidazole; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃;

benzyl bromide; In N,N-dimethyl-formamide; Further stages.;

DOI:10.1016/j.tetlet.2004.05.011

upstream raw materials:

benzyl chloride

4-iodoimidazole

benzyl bromide

Downstream raw materials:

1-benzyl-5-vinyl-1H-imidazole

1-benzyl-5-(4-(1-benzyl-1H-imidazol-5-yl)buta-1,3-diynyl)-1H-imidazole

Refernces

• 1、 He, Yong,Chen, Yingzhong,Du, Hongwang,Schmid, Lesley A.,Lovely, Carl J.. "A convenient synthesis of 1,4-disubstituted imidazoles". . p. 5529 - 5532. Retrieved 2007/10/03.