Diethylamine hydrobromide

Base Information

• Chemical Name: Diethylamine hydrobromide
• CAS No.: 6274-12-0
• Molecular Formula: C4H12BrN
• Molecular Weight: 154.05
• Hs Code.: 2921 19 50
• European Community (EC) Number: 228-466-2
• NSC Number: 35762
• DSSTox Substance ID: DTXSID80878709
• Mol file: 6274-12-0.mol

Synonyms:diethylamine;diethylamine acetate;diethylamine hydrobromide;diethylamine hydrochloride;diethylamine perchlorate;diethylamine phosphate (1:1);diethylamine sulfate;diethylamine sulfite (1:1)

Chemical Property of Diethylamine hydrobromide

Chemical Property:

• Appearance/Colour: white powder
• Melting Point: 218-220 °C
• Boiling Point: 57.3 °C at 760 mmHg
• Flash Point: 23.1 °C
• PSA: 12.03000
• LogP: 1.96480
• Storage Temp.: Store below +30°C.
• Sensitive.: Hygroscopic
• Water Solubility.: Soluble in water
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 153.01531
• Heavy Atom Count: 6
• Complexity: 11.1

Purity/Quality:

99.5% ^*data from raw suppliers

Diethylamine hydrobromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCNCC.Br
• Uses: Diethylamine hydrobromide was used in the synthesis of α-bromovinyltrimethylsilane.

Technology Process of Diethylamine hydrobromide

There total 27 articles about Diethylamine hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

bis(diethylamino)phenylphosphine(pentacarbonyl)tungsten(0) (126306-20-5) → bromodiethylaminophenylphosphine(pentacarbonyl)tungsten(0) (126289-68-7) + diethylamine hydrobromide (6274-12-0)

Guidance literature:

With hydrogen bromide; In pentane; Under stirring a strong stream of hydrogenhalogenide is bubbled for 3-10 min through the cooled (-50-0°C) soln. of phosphine complex (inert atmosphere).; Solvent is evapd. at room temp. in vac., residue is digested with pentane, dialkylamminhydrohalogenide is filtered off, filtrate is dried to dryness in vac., recrystn. from pentane (-78°C), not purely isolated.;

DOI:10.1016/0022-328X(89)85002-8

Reference yield: 84.0%

bis(diethylamino)-(-)-menthylphosphine(pentacarbonyl)chromium(0) → bromoodiethylamino-(-)-menthylphosphine(pentacarbonyl)chromium(0) + diethylamine hydrobromide (6274-12-0)

Guidance literature:

With hydrogen bromide; In pentane; Under stirring a strong stream of hydrogenhalogenide is bubbled for 10 min through the cooled (0°C) soln. of phosphine complex (inert atmosphere).; Solvent is evapd. at room temp. in vac., residue is digested with pentane, dialkylamminhydrohalogenide is filtered off, filtrate is dried to dryness in vac., recrystn. from pentane (-78°C), elem. anal.;

DOI:10.1016/0022-328X(89)85002-8

Reference yield: 80.0%

bis(diethylamin)nickeldibromid (14873-98-4) + diethylamine (109-89-7) → N-formyldiethylamine (617-84-5) + N,N,N',N'-tetraethylurea (1187-03-7) + N,N,N',N'-tetraethyloxamide (14288-05-2) + diethylamine hydrobromide (6274-12-0) + tetracarbonyl nickel (13463-39-3,71564-36-8)

Guidance literature:

With carbon monoxide; In tetrahydrofuran; diethyl ether; reaction in THF/Et2O = 2/1 soln., room temp., under CO (1 bar);

DOI:10.1016/S0022-328X(00)99113-7

upstream raw materials:

bis((N,N-diethyl)amino)vinylphosphine

3-bromo-1-phenylpropan-1-one

diethylamine

1-ethyl-2-bromo-pyridinium; bromide

Downstream raw materials:

N,N,N',N'-tetraethyl-guanidine

1,1-Diphenyl-5-diethylamino-pentin-⁽³⁾-ol-⁽¹⁾

(E)-5-Diethylamino-1-p-tolyl-pent-1-en-3-one; hydrobromide

N,N-diethylphenacylamine

Refernces

• 1、 Diemert, K.,Kuchen, W.,Lorenzen, D.. "Reaktionen koordinierter Liganden V. Pentacarbonylhalogenaminophosphinkomplexe (CO)5MPRXNR'2 durch Umsetzung von (CO)5MPR(NR'2)2 mit Halogenwasserstoff". . p. 17 - 32. Retrieved 2007/10/02.
• 2、 Son, Tae-il,Yanagihara, Hisayoshi,Ozawa, Fumiyuki,Yamamoto, Akio. "Palladium-Catalyzed Double-Carbonylation of Alkenyl Halides with Secondary Amines to Give α-Keto Amides". . p. 1251 - 1258. Retrieved 2007/10/02.