3-chloro-4-methoxybenzamide

Base Information

• Chemical Name: 3-chloro-4-methoxybenzamide
• CAS No.: 89978-93-8
• Molecular Formula: C8H8ClNO2
• Molecular Weight: 185.61
• Mol file: 89978-93-8.mol

Synonyms:SALOR-INT L480983-1EA;3-CHLORO-4-METHOXYBENZAMIDE

Chemical Property of 3-chloro-4-methoxybenzamide

Chemical Property:

• Vapor Pressure: 0.00296mmHg at 25°C
• Boiling Point: 284.5°C at 760 mmHg
• Flash Point: 125.9°C
• Density: 1.288g/cm³

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-chloro-4-methoxybenzamide

There total 5 articles about 3-chloro-4-methoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 3-chloro-p-anisate (37908-98-8) → 3-chloro-4-methoxy-benzoic acid amide (89978-93-8)

Guidance literature:

Multi-step reaction with 3 steps

1: KOH / methanol

2: thionyl chloride

3: aq.ammonia

With potassium hydroxide; ammonium hydroxide; thionyl chloride; In methanol;

DOI:10.1002/jps.2600750420

Reference yield:

3-chloro-4-methoxybenzoyl chloride (36590-49-5) → 3-chloro-4-methoxy-benzoic acid amide (89978-93-8)

Guidance literature:

With ammonium hydroxide;

DOI:10.1002/jps.2600750420

Reference yield:

3-chloro-4-methoxy benzoic acid (37908-96-6) → 3-chloro-4-methoxy-benzoic acid amide (89978-93-8)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride

2: aq.ammonia

With ammonium hydroxide; thionyl chloride;

DOI:10.1002/jps.2600750420

upstream raw materials:

cyanic acid

2-Chloroanisole

3-chloro-4-methoxybenzoyl chloride

3-chloro-4-methoxy benzoic acid

Downstream raw materials:

3-chloro-4-methoxy benzoic acid

3-Chloro-4-methoxybenzonitrile

2-Bromo-1-(3-chloro-4-methoxy-phenyl)-propan-1-one

1-(3'-chloro-4'-methoxyphenyl)-1-propanone

Refernces