Benzoylcholine Chloride

Base Information

• Chemical Name: Benzoylcholine Chloride
• CAS No.: 29640-90-2
• Molecular Formula: C12H18ClNO2
• Molecular Weight: 195.175
• Hs Code.: 2916399090
• Mol file: 29640-90-2.mol

Synonyms:4-Methyl-2-nitrophenylessigsaeure;(4-Methyl-2-nitrophenyl)-essigsaeure;(4-methyl-2-nitro-phenyl)-acetic acid;(4-Methyl-2-nitro-phenyl)-essigsaeure;

Chemical Property of Benzoylcholine Chloride

Chemical Property:

• PSA: 83.12000
• LogP: 2.05350

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoylcholine Chloride

There total 13 articles about Benzoylcholine Chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

4-tolylacetic acid (622-47-9) → (4-methyl-2-nitro-phenyl)-acetic acid (29640-90-2)

Guidance literature:

With ammonium nitrate; trifluoroacetic anhydride; In chloroform;

DOI:10.1016/j.bmcl.2005.06.097

Reference yield:

2,2'-(2-nitro-1,4-phenylene)diacetic acid (1455471-51-8) → mononitro-p-xylene (89-58-7) + (4-methyl-2-nitro-phenyl)-acetic acid (29640-90-2) + 2-nitro-4-methylbenzaldehyde (20357-22-6)

Guidance literature:

With sodium hydroxide; In water-d2; at 23 ℃; Photolysis;

DOI:10.1002/chem.201901213

Reference yield:

1,4-phenylenediacetic acid (7325-46-4) → mononitro-p-xylene (89-58-7) + (4-methyl-2-nitro-phenyl)-acetic acid (29640-90-2) + 2-nitro-4-methylbenzaldehyde (20357-22-6)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid; nitric acid / 1 h / 0 °C / Darkness

2: sodium hydroxide / water-d2 / 23 °C / Photolysis

With sulfuric acid; nitric acid; sodium hydroxide; In water-d2;

DOI:10.1002/chem.201901213

upstream raw materials:

(4-methyl-2-nitro-phenyl)-pyruvic acid

4-tolylacetic acid

2-nitro-4-methylbenzaldehyde

4-methyl-2-nitrophenylacetaldehyde

Downstream raw materials:

methyl 2-(4-methyl-2-nitrophenyl)acetate

methyl 1-[4-(1-methoxy-1-oxopropan-2-yl)-3-nitrobenzyl]-2-oxocyclopentanecarboxylate

sodium 2-{2-nitro-4-[(2-oxocyclopentyl)methyl]phenyl}propanoate

methyl 2-(4-methyl-2-nitrophenyl)propanoate

Refernces

• 1、 Yamakawa, Naoki,Suemasu, Shintaro,Matoyama, Masaaki,Tanaka, Ken-Ichiro,Katsu, Takashi,Miyata, Keishi,Okamoto, Yoshinari,Otsuka, Masami,Mizushima, Tohru. "Synthesis and biological evaluation of loxoprofen derivatives". . p. 3299 - 3311. Retrieved 2011/07/08.