Butyl mandelate

Base Information

• Chemical Name: Butyl mandelate
• CAS No.: 119718-90-0
• Molecular Formula: C₁₂H₁₆O₃
• Molecular Weight: 208.257
• Mol file: 119718-90-0.mol

Synonyms:butyl mandelate

Chemical Property of Butyl mandelate

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Butyl mandelate

There total 24 articles about Butyl mandelate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

MANDELIC ACID (611-71-2,611-72-3,17199-29-0,90-64-2) + butan-1-ol (71-36-3) → butyl mandelate (14007-02-4,119718-90-0)

Guidance literature:

With thionyl chloride; at 20 ℃; for 4h;

DOI:10.1039/c6ra25562k

Reference yield: 94.0%

2,5-diphenyl-[1,3]dioxolan-4-one (56535-98-9) + butan-1-ol (71-36-3) → butyl mandelate (14007-02-4,119718-90-0)

Guidance literature:

With MANDELIC ACID; In toluene; at 80 ℃; for 10h; chemoselective reaction; Inert atmosphere;

DOI:10.1039/c2ra23068b

Reference yield: 87.0%

phenylglyoxal hydrate (1074-12-0) + butan-1-ol (71-36-3) → butyl mandelate (14007-02-4,119718-90-0)

Guidance literature:

With silica-alumina powder 70 mol% Al2O3; at 89.84 ℃; for 4h; chemoselective reaction; Mechanism;

DOI:10.1021/cs400271e

upstream raw materials:

phenylglyoxal hydrate

butan-1-ol

MANDELIC ACID

diphenyl cadmium

Downstream raw materials:

(R)-mandelic acid n-butyl ester

(S)-butyl 2-acetoxy-2-phenylethanoate

(R)-(-)-butyl O-acetylmandelate

n-butyl 2-oxo-2-phenylacetate

Refernces

• 1、 Zhang, Gui-Sheng,Gong, Hui. "Fe2(SO4)3 · xH2O in synthesis: A new and convenient catalyst for the esterification of mandelic acid with alcohols". . p. 1547 - 1551. Retrieved 1999.
• 2、 Keshavarz, Mosadegh,Iravani, Nasir,Parhami, Abolfath. "Novel SO3H-functionalized polyoxometalate-based ionic liquids as highly efficient catalysts for esterification reaction". . p. 272 - 278. Retrieved 2019/04/25.
• 3、 Talsi, Evgenii P.,Bryliakov, Konstantin P.. "Autoamplification-Enhanced Oxidative Kinetic Resolution of sec-Alcohols and Alkyl Mandelates, and its Kinetic Model". . p. 2693 - 2699. Retrieved 2018/06/26.