Technology Process of 3-Bromo-5-isobutoxybenzoic acid
There total 6 articles about 3-Bromo-5-isobutoxybenzoic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
3-bromo-5-isobutoxy-benzoic acid isobutyl ester;
With
methanol; sodium hydroxide;
at 50 ℃;
for 2h;
With
hydrogenchloride;
In
water;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sodium hydrogencarbonate; sodium hydroxide / 1,4-dioxane; water / 12 h / 20 °C
2: potassium carbonate / N,N-dimethyl-formamide / 12 h / 40 - 50 °C
3: trifluoroacetic acid / dichloromethane / 12 h / 20 °C
4: copper(I) bromide; sodium nitrite; hydrogen bromide / ethanol; water / 0.33 h / 0 - 90 °C
5: sodium hydroxide; methanol / 2 h / 50 °C
With
methanol; hydrogen bromide; sodium hydrogencarbonate; potassium carbonate; trifluoroacetic acid; copper(I) bromide; sodium hydroxide; sodium nitrite;
In
1,4-dioxane; ethanol; dichloromethane; water; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: copper(I) bromide; sodium nitrite; hydrogen bromide / ethanol; water / 0.33 h / 0 - 90 °C
2: sodium hydroxide; methanol / 2 h / 50 °C
With
methanol; hydrogen bromide; copper(I) bromide; sodium hydroxide; sodium nitrite;
In
ethanol; water;
