Technology Process of 3-bromo-5-isobutoxy-benzoic acid isobutyl ester
There total 5 articles about 3-bromo-5-isobutoxy-benzoic acid isobutyl ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogen bromide; copper(I) bromide; sodium nitrite;
In
ethanol; water;
at 0 - 90 ℃;
for 0.333333h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 40 - 50 °C
2: trifluoroacetic acid / dichloromethane / 12 h / 20 °C
3: copper(I) bromide; sodium nitrite; hydrogen bromide / ethanol; water / 0.33 h / 0 - 90 °C
With
hydrogen bromide; potassium carbonate; trifluoroacetic acid; copper(I) bromide; sodium nitrite;
In
ethanol; dichloromethane; water; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: ammonium hydroxide; ammonium chloride / 72 h / 180 °C / Autoclave
1.2: 24 h / 100 °C
2.1: sodium hydrogencarbonate; sodium hydroxide / 1,4-dioxane; water / 12 h / 20 °C
3.1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 40 - 50 °C
4.1: trifluoroacetic acid / dichloromethane / 12 h / 20 °C
5.1: copper(I) bromide; sodium nitrite; hydrogen bromide / ethanol; water / 0.33 h / 0 - 90 °C
With
ammonium hydroxide; hydrogen bromide; sodium hydrogencarbonate; potassium carbonate; ammonium chloride; trifluoroacetic acid; copper(I) bromide; sodium hydroxide; sodium nitrite;
In
1,4-dioxane; ethanol; dichloromethane; water; N,N-dimethyl-formamide;
