6-Hydroxyheptanoic acid ethyl ester

Base Information

• Chemical Name: 6-Hydroxyheptanoic acid ethyl ester
• CAS No.: 55099-47-3
• Molecular Formula: C₉H₁₈O₃
• Molecular Weight: 174.24
• Mol file: 55099-47-3.mol

Synonyms:6-Hydroxyenanthic acid ethyl ester;6-Hydroxyheptanoic acid ethyl ester

Chemical Property of 6-Hydroxyheptanoic acid ethyl ester

Chemical Property:

• Boiling Point: 91 - 96 °C (0.750075 - 2.17522 mmHg)
• PSA: 46.53000
• LogP: 1.49070

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Hydroxyheptanoic acid ethyl ester

There total 10 articles about 6-Hydroxyheptanoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

ethyl 6-heptenoate (25118-23-4) → (+/-)-Ethyl 6-hydroxyheptanoate (55099-47-3)

Guidance literature:

With dichloro bis(acetonitrile) palladium(II); 1-hydroxytetraphenyl-cyclopentadienyl(tetraphenyl-2,4-cyclopentadien-1-one)-μ-hydrotetracarbonyldiruthenium(II); water; p-benzoquinone; In methanol; isopropyl alcohol; at 85 ℃; for 48h; regioselective reaction; Inert atmosphere; Glovebox;

DOI:10.1039/c3cc48810a

Reference yield:

→ (+/-)-Ethyl 6-hydroxyheptanoate (55099-47-3)

Guidance literature:

With platinum(IV) oxide; ethanol; Hydrogenation;

Reference yield:

7-methyl-2-oxepanone (2549-59-9) + conc. H2 SO4 + 6-hydroxyheptanoic acid (21961-03-5) → (+/-)-Ethyl 6-hydroxyheptanoate (55099-47-3)

Guidance literature:

In ethanol;

upstream raw materials:

ethanol

methyl 6-oxoheptanoate

ethyl 6-oxoheptanoate

7-methyl-2-oxepanone

Downstream raw materials:

ethyl 6-oxoheptanoate

(S)-(-)-N-[4-[4-[Ethyl(6-fluoroheptyl)amino]-1-hydroxybutyl]phenyl]-methanesulfonamide

Phthalic acid mono-((S)-5-ethoxycarbonyl-1-methyl-pentyl) ester

S-(+)-Ethyl 6-phthaloxyheptanoate

Refernces

• 1、 Yang, Yongsheng,Guo, Jiayi,Ng, Huimin,Chen, Zhiyong,Teo, Peili. "Formal hydration of non-activated terminal olefins using tandem catalysts". supporting information. p. 2608 - 2611. Retrieved 2014/03/21.
• 2、 Sato, Kazuhiko,Aoki, Masao,Takagi, Junko,Zimmermann, Klaus,Noyori, Ryoji. "A practical method for alcohol oxidation with aqueous hydrogen peroxide under organic solvent- and halide-free conditions". . p. 2287 - 2306. Retrieved 2007/10/03.