Doxefazepam

Base Information

• Chemical Name: Doxefazepam
• CAS No.: 40762-15-0
• Molecular Formula: C17H14 Cl F N2 O3
• Molecular Weight: 348.761
• UNII: 231RV72C8L
• DSSTox Substance ID: DTXSID2020551
• Nikkaji Number: J16.569G
• Wikipedia: Doxefazepam
• Wikidata: Q3714813
• NCI Thesaurus Code: C65474
• Metabolomics Workbench ID: 154615
• ChEMBL ID: CHEMBL64677
• Mol file: 40762-15-0.mol

Synonyms:1-(2-hydroxyethyl)-3-hydroxy-7-chloro-1,3-dihydro-5-(o-fluorophenyl)-2H-1,4-benzodiazepin-2-one;doxefazepam;SAS 643

Chemical Property of Doxefazepam

Chemical Property:

• Vapor Pressure: 3.77E-16mmHg at 25°C
• Boiling Point: 618.4°Cat760mmHg
• Flash Point: 327.8°C
• PSA: 73.13000
• Density: 1.45g/cm³
• LogP: 1.47440
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 348.0676982
• Heavy Atom Count: 24
• Complexity: 504

Purity/Quality:

95-99% ^*data from raw suppliers

Doxefazepam ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)C2=NC(C(=O)N(C3=C2C=C(C=C3)Cl)CCO)O)F
• Description: Doxefazepam is a benzodiazepine hypnotic somewhat more potent than flurazepam.

Technology Process of Doxefazepam

There total 1 articles about Doxefazepam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ doxefaxepam (40762-15-0)

Guidance literature:

aus dem Diacetat (II) mit methanol. NH3;

DOI:10.1111/j.2042-7158.1974.tb09345.x

Refernces

• 1、 Tamagnone,Torrielli,De Marchi. "A new benzodiazepine: 1 (2 hydroxyethyl) 3 hydroxy 7 chloro 1,3 dihydro 5 (o fluorophenyl) 2H 1,4 benzodiazepin 2 one". . p. 566 - 567. Retrieved 2007/10/09.