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CAS No.: | 40762-15-0 |
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Name: | Doxefazepam |
Article Data: | 3 |
Molecular Structure: | |
Formula: | C17H14 Cl F N2 O3 |
Molecular Weight: | 348.761 |
Synonyms: | 1-(2-Hydroxyethyl)-3-hydroxy-7-chloro-1,3-dihydro-5-(o-fluorophenyl)-2H-1,4-benzodiazepin-2-one;Doxans; Doxefazepam; N-1-Hydroxyethyl-3-hydroxyflurazepam; SAS 643 |
Density: | 1.45g/cm3 |
Boiling Point: | 618.4°Cat760mmHg |
Flash Point: | 327.8°C |
Safety: | Moderately toxic by ingestion and intraperitoneal routes. Human systemic effects by an unspecified route: somnolence. When heated to decomposition it emits very toxic fumes of Cl−, F−, and NOx. |
PSA: | 73.13000 |
LogP: | 1.47440 |
1. | unr-hmn TDLo:71 µg/kg:CNS | DRFUD4 Drugs of the Future. 3 (1978),145. | ||
2. | orl-rat LD50:2550 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 25 (1975),1294. | ||
3. | ipr-rat LD50:586 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 25 (1975),1294. | ||
4. | ipr-mus LD50:760 mg/kg | JPPMAB Journal of Pharmacy and Pharmacology. 26 (1974),566. |