spicatosideB

Base Information

• Chemical Name: spicatosideB
• CAS No.: 87425-34-1
• Molecular Formula: C39H62O12
• Molecular Weight: 722.914
• Mol file: 87425-34-1.mol

Synonyms:spicatosideB;(1beta,3beta,25S)-3-[(6-Deoxy-alpha-L-mannopyranosyl)oxy]spirost-5-en-1-yl 6-deoxy-beta-D-galactopyranoside;Nolinospiroside F;LP-B

Chemical Property of spicatosideB

Chemical Property:

• PSA: 176.76000
• LogP: 2.38830

Purity/Quality:

≥97% ^*data from raw suppliers

NolinospirosideF 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Liriopesides B is the main saponin content in Hubei liriope (Liriope spicata var. prolifera). Liriopesides B exhibites potential anticancer activity against human ovarian cancer A2780 cells.

Technology Process of spicatosideB

There total 1 articles about spicatosideB which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

lirioplioside A → (25S)-spirost-5-ene-1β,3β-diol 1-O-β-D-fucopyranoside 3-O-α-L-rhamnopyranoside (87425-34-1) + 25(S)-ruscogenin 1-O-α-L-rhamnopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→3)]-β-D-fucopyranoside (41753-55-3) + 25(S)-ruscogenin (874485-32-2)

Guidance literature:

With hydrogenchloride; In methanol; water; at 80 ℃; for 0.5h;

DOI:10.1016/0031-9422(96)00228-2

Reference yield:

25(S)-ruscogenin 1-O-β-D-fucopyranosido-3-O-α-L-rhamnopyranoside (87425-34-1) → 25(S)-ruscogenin (472-11-7,35882-30-5,66251-06-7,79037-17-5,119008-55-8,874485-32-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 0.2 N H₂SO₄ / ethanol / 5 h / 60 °C / Heating

2: 2 N HCl / dioxane

With hydrogenchloride; sulfuric acid; In 1,4-dioxane; ethanol;

Reference yield:

25(S)-ruscogenin 1-O-β-D-fucopyranosido-3-O-α-L-rhamnopyranoside (87425-34-1) → L-rhamnose (73-34-7) + D-Fucose (73-34-7,87-96-7,488-79-9,551-63-3,609-01-8,643-17-4,643-18-5,4164-09-4,6014-42-2,6155-36-8,6189-71-5,6696-41-9,6736-43-2,13224-93-6,22611-09-2,28161-49-1,28161-50-4,28161-52-6,45864-36-6,63814-64-2,71116-59-1,71116-61-5,72598-05-1,87936-88-7,87936-89-8,97466-79-0,116908-82-8,120442-60-6,123484-22-0,133576-32-6) + 25(S)-ruscogenin (472-11-7,35882-30-5,66251-06-7,79037-17-5,119008-55-8,874485-32-2)

Guidance literature:

With hydrogenchloride; for 3h; Heating;

Downstream raw materials:

(2R,3R,4S,5R,6R)-6-Methyl-tetrahydro-pyran-2,3,4,5-tetraol

L-rhamnose

25(S) ruscogenin

L-rhamnose

Refernces