3-METHYL-1,3,4,5,7,8-HEXAHYDRO-2,6-QUINOLINEDIONE

Base Information

• Chemical Name: 3-METHYL-1,3,4,5,7,8-HEXAHYDRO-2,6-QUINOLINEDIONE
• CAS No.: 77903-18-5
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.219
• Hs Code.: 2933499090
• Mol file: 77903-18-5.mol

Synonyms:3-METHYL-1,3,4,5,7,8-HEXAHYDRO-2,6-QUINOLINEDIONE;3-Methyl-3,4,7,8-tetrahydro-2,5(1H,6H)-quinolinedione

Chemical Property of 3-METHYL-1,3,4,5,7,8-HEXAHYDRO-2,6-QUINOLINEDIONE

Chemical Property:

• Melting Point: 206-208°C
• PSA: 46.17000
• LogP: 1.47830

Purity/Quality:

98%min ^*data from raw suppliers

3-methyl-1,2,3,4,5,6,7,8-octahydroquinoline-2,6-dione ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-METHYL-1,3,4,5,7,8-HEXAHYDRO-2,6-QUINOLINEDIONE

There total 1 articles about 3-METHYL-1,3,4,5,7,8-HEXAHYDRO-2,6-QUINOLINEDIONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

poly(methacrylic acid) (79-41-4,25087-26-7,50867-57-7) + 3-amino-cyclohex-2-enone (5220-49-5) → 3-methyl-1,2,3,4,5,6,7,8-octahydroquinoline-2,5-dione (77903-18-5)

Guidance literature:

at 180 ℃; for 3h;

DOI:10.1021/jo00331a027

Reference yield: 100.0%

3-methyl-1,2,3,4,5,6,7,8-octahydroquinoline-2,5-dione (77903-18-5) → 5-hydroxy-3-methyl-2(1H)-quinolinone (177938-27-1)

Guidance literature:

palladium on activated charcoal; In decalin; for 96h; Heating;

DOI:10.3987/com-95-7366

upstream raw materials:

poly(methacrylic acid)

3-amino-cyclohex-2-enone

Downstream raw materials:

5-hydroxy-3-methyl-2(1H)-quinolinone

Refernces

• 1、 Shono, Tatsuya,Matsumura, Yoshihiro,Kashimura, Shigenori. "A New Practical Synthesis of 5-Hydroxy-3,4-dihydrocarbostyril and 5-Hydroxycarbostyril". . p. 3719. Retrieved 2007/10/02.