3-Hydroxyquinoline

Base Information Edit

Chemical Name:3-Hydroxyquinoline
CAS No.:580-18-7
Molecular Formula:C9H7 N O
Molecular Weight:145.161
Hs Code.:2933499090
European Community (EC) Number:209-456-7
UNII:12PZ582CI0
DSSTox Substance ID:DTXSID00206727
Nikkaji Number:J101.386F
Wikidata:Q27251431
ChEMBL ID:CHEMBL3236920
Mol file:580-18-7.mol

Synonyms:3-Hydroxyquinoline;580-18-7;Quinolin-3-ol;3-QUINOLINOL;3-Quinolol;CCRIS 4328;EINECS 209-456-7;MFCD00169018;BRN 0113185;UNII-12PZ582CI0;12PZ582CI0;5-21-03-00224 (Beilstein Handbook Reference);3-hydroxychinolin;Quinolin-3-o1;3-hydroxy-quinoline;Oprea1_711388;SCHEMBL133799;3-hydroxyquinoline, AldrichCPR;CHEMBL3236920;DTXSID00206727;AMY32106;BCP20129;BBL104199;STL558030;AKOS003602545;CS-W008203;SB67484;AC-22551;AS-18424;SY009024;LS-142471;A8246;FT-0600267;Q0094;EN300-98107;AE-907/30839031;Q27251431;Z1255419538

Suppliers and Price of 3-Hydroxyquinoline

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Hydroxyquinoline
5g
$ 110.00

TCI Chemical
3-Quinolinol >98.0%(GC)(T)
5g
$ 227.00

TCI Chemical
3-Quinolinol >98.0%(GC)(T)
1g
$ 67.00

Medical Isotopes, Inc.
3-Hydroxyquinoline
1 g
$ 565.00

Medical Isotopes, Inc.
3-Hydroxyquinoline
5 g
$ 610.00

Matrix Scientific
3-Hydroxyquinoline 95+%
25g
$ 249.00

Matrix Scientific
3-Hydroxyquinoline 95+%
5g
$ 64.00

Matrix Scientific
3-Hydroxyquinoline 95+%
1g
$ 14.00

Crysdot
3-Hydroxyquinoline 97%
25g
$ 222.00

Crysdot
3-Hydroxyquinoline 97%
100g
$ 673.00

Total 77 raw suppliers

Chemical Property of 3-Hydroxyquinoline Edit

Chemical Property:

Vapor Pressure:0.000278mmHg at 25°C
Melting Point:198-202°C
Refractive Index:1.4500 (estimate)
Boiling Point:313oC at 760 mmHg
PKA:4.28(at 20℃)
Flash Point:143.1oC
PSA：33.12000
Density:1.26g/cm3
LogP:1.94040
Storage Temp.:Inert atmosphere,Room Temperature
Solubility.:DMSO (Slightly), Methanol (Slightly)
Water Solubility.:587.9mg/L(20 oC)
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:145.052763847
Heavy Atom Count:11
Complexity:138

Purity/Quality:

99% ^*data from raw suppliers

3-Hydroxyquinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=C(C=N2)O
Uses 3-Hydroxyquinoline is a chemical reagent used in the preparation cyclic peptides with an antitumor functionality. Quinoline derivative as a result of the metabolism by cytochrome P 450.

Technology Process of 3-Hydroxyquinoline

There total 20 articles about 3-Hydroxyquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 612-59-9
3-chloroquinoline

: 580-18-7
3-hydroxyquinoline

Guidance literature:: With 2-di-tertbutylphosphino-3,4,5,6-tetramethyl-2',4',6'-triisopropyl-1,1'-biphenyl; potassium hydroxide; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In 1,4-dioxane; water; at 100 ℃; for 17h;
DOI:10.1021/ja0639719

Reference yield: 96.0%

: 5332-24-1
3-bromoquinoline

: 580-18-7
3-hydroxyquinoline

Guidance literature:: With copper acetylacetonate; N¹-(4-hydroxy-2,6-dimethylphenyl)-N²-(4-hydroxy-3,5-dimethylphenyl)oxalamide; water; In water; dimethyl sulfoxide; at 80 ℃; for 24h; Schlenk technique; Inert atmosphere;
DOI:10.1021/jacs.6b08114