N-ForMyl Oxcarbazepine

Base Information

• Chemical Name: N-ForMyl Oxcarbazepine
• CAS No.: 1346601-76-0
• Molecular Formula: C₁₆H₁₂N₂O₃
• Molecular Weight: 280.283
• Mol file: 1346601-76-0.mol

Synonyms:N-ForMyl Oxcarbazepine;N-ForMyl-10,11-dihydro-10-oxo-;Oxcarbazepine Related CoMpound A;N-Formyl-10-oxo-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide

Chemical Property of N-ForMyl Oxcarbazepine

Chemical Property:

• PKA: 9.17±0.20(Predicted)
• PSA: 69.97000
• Density: 1.342±0.06 g/cm3(Predicted)
• LogP: 3.33480
• Storage Temp.: -20°C Freezer
• Solubility.: Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slig

Purity/Quality:

95% min ^*data from raw suppliers

N-FormylOxcarbazepine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N-Formyl Oxcarbazepine is an impurity of the anticonvulsant Oxcarbazepine (O869250).

Technology Process of N-ForMyl Oxcarbazepine

There total 2 articles about N-ForMyl Oxcarbazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

10-methoxy-5H-dibenzo[b,f]azepine (4698-11-7) → N-formyl oxcarbazepine (1346601-76-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: dichloromethane / 0 - 25 °C

1.2: 60 - 65 °C

2.1: acetic anhydride / 2 h / 25 - 60 °C

With acetic anhydride; In dichloromethane;

DOI:10.1002/jhet.4281

Reference yield:

formic acid (64-18-6) + oxcarbazepine (28721-07-5) → N-formyl oxcarbazepine (1346601-76-0)

Guidance literature:

With acetic anhydride; at 25 - 60 ℃; for 2h;

DOI:10.1002/jhet.4281

upstream raw materials:

formic acid

oxcarbazepine

10-methoxy-5H-dibenzo[b,f]azepine

Refernces