Triethyl citrate

Base Information Edit

Chemical Name:Triethyl citrate
CAS No.:77-93-0
Molecular Formula:C12H20O7
Molecular Weight:276.287
Hs Code.:2918 15 00
European Community (EC) Number:201-070-7,629-703-6
ICSC Number:1350
NSC Number:8907
UNII:8Z96QXD6UM
DSSTox Substance ID:DTXSID0040701
Nikkaji Number:J4.215C
Wikipedia:Triethyl_citrate
Wikidata:Q418057
NCI Thesaurus Code:C76736
RXCUI:1310554
Metabolomics Workbench ID:46460
ChEMBL ID:CHEMBL464988
Mol file:77-93-0.mol

Synonyms:ethyl citrate;triethyl citrate

Suppliers and Price of Triethyl citrate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
TEC
48Tests
$ 588.00

TRC
Triethyl citrate
50g
$ 125.00

TCI Chemical
Triethyl Citrate >99.0%(GC)
500g
$ 57.00

TCI Chemical
Triethyl Citrate >99.0%(GC)
25g
$ 16.00

Sigma-Aldrich
Triethyl citrate ≥99%, FCC, FG
1 kg
$ 84.00

Sigma-Aldrich
Triethyl citrate natural, ≥99%, FG
1kg-k
$ 84.00

Sigma-Aldrich
Triethyl citrate ≥99%, FCC, FG
1kg-k
$ 84.00

Sigma-Aldrich
Triethyl citrate Pharmaceutical Secondary Standard; Certified Reference Material
1g
$ 72.80

Sigma-Aldrich
Triethyl citrate for synthesis. CAS 77-93-0, EC Number 201-070-7, chemical formula HOC(COOC H )(CH COOC H ) ., for synthesis
8002510500
$ 60.90

Sigma-Aldrich
Triethyl citrate for synthesis
500 mL
$ 58.37

Total 187 raw suppliers

Chemical Property of Triethyl citrate Edit

Chemical Property:

Appearance/Colour:clear liquid
Vapor Pressure:1 mm Hg ( 107 °C)
Melting Point:-46 °C
Refractive Index:n20/D 1.442(lit.)
Boiling Point:294 °C at 760 mmHg
PKA:11.57±0.29(Predicted)
Flash Point:95.4 °C
PSA：99.13000
Density:1.177 g/cm³
LogP:0.18700
Storage Temp.:-20°C
Solubility.:H2O: soluble
Water Solubility.:5.7 g/100 mL (25 ºC)
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:11
Exact Mass:276.12090297
Heavy Atom Count:19
Complexity:304

Purity/Quality:

99% ^*data from raw suppliers

TEC ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 20
Safety Statements: 24/25-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Other Classes -> Other Organic Compounds
Canonical SMILES:CCOC(=O)CC(CC(=O)OCC)(C(=O)OCC)O
Recent ClinicalTrials:Phase II Study of Tislelizumab Combined With Cetuximab and Irinotecan in the Treatment of Recurrent, Refractory mCRC
Recent EU Clinical Trials:A randomized trial of adjuvant treatment with radiation plus chemotherapy versus radiation alone in high-risk endometrial carcinoma NSGO-EC-9501 Amendment 2.
Inhalation Risk:A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20 °C.
Effects of Short Term Exposure:The substance is irritating to the eyes and respiratory tract.
Description Triethyl citrate is the triester of citric acid and ethyl alcohol. Triethyl citrate is used as a flavoring agent in foods, as a high boiling solvent and plasticizer for vinyl resins and cellulose acetates, as a plasticizer in the pharmaceutical industry for coating. Triethyl citrate is used as a natural active ingredient and flavor component with excellent deodorizing and skin care properties in cosmetic and personal care products. Triethyl citrate is also used as a plasticizer and humectant for cigarette filters. Furthermore, triethyl citrate is used s a food additive for stabilizing foams, specifically as a whipping enhancer for organic egg whites during processing.
Uses Triethyl Citrate, is a colorless, odorless liquid used as a food additive to stabilize foams, especially as whipping aid for egg white. It is also used in pharmaceutical coatings and plastics. This compound is a contaminant of emerging concern (CECs). Triethyl Citrate is a sequestrant that is an oily liquid, slightly solu- ble in water. it is found in lemon drinks.

Technology Process of Triethyl citrate

There total 15 articles about Triethyl citrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 64-17-5
ethanol

: 77-92-9,906507-37-7
citric acid

: 77-93-0
citric acid triethyl ester

Guidance literature:: ethanol; With dicyclohexyl-carbodiimide; at 20 ℃; for 36h; Large scale;

citric acid; at 35 ℃; for 6h; Temperature; Autoclave; Large scale;