2-Methylcinnamic Acid

Base Information Edit

Chemical Name:2-Methylcinnamic Acid
CAS No.:939-57-1
Molecular Formula:C₁₀H₁₀O₂
Molecular Weight:162.188
Hs Code.:
European Community (EC) Number:219-150-5
NSC Number:99069
DSSTox Substance ID:DTXSID80901046
Nikkaji Number:J135.443D,J213.235D
ChEMBL ID:CHEMBL1771751
Mol file:939-57-1.mol

Synonyms:2-Methylcinnamic Acid;2373-76-4;939-57-1;o-Methylcinnamic acid;3-(o-Tolyl)acrylic acid;(E)-3-(o-Tolyl)acrylic acid;(E)-3-(2-methylphenyl)prop-2-enoic acid;2-Methylcinnamic acid, predominantly trans;(2E)-3-(2-methylphenyl)acrylic acid;2-Methylcinnamicacid;(2E)-3-(2-methylphenyl)prop-2-enoic acid;(E)-3-(2-Methylphenyl)-2-propenoic acid;(E)-3-o-tolylacrylic acid;MFCD00016841;EINECS 219-150-5;3-(2-methylphenyl)prop-2-enoic acid;Cinnamic acid, o-methyl-, (E)-;3-(2-methylphenyl)acrylic acid;NoName_96;2-Propenoic acid, 3-(2-methylphenyl)-, (E)-;2-Methylbenzeneacrylic acid;trans-2-methylcinnamic acid;SCHEMBL78555;(E)-3-o-tolyl-acrylic acid;(E)-3-(o-Tolyl)acrylicacid;CHEMBL1771751;RSWBWHPZXKLUEX-VOTSOKGWSA-;DTXSID80901046;CHEBI:181430;NSC99069;BBL013455;NSC 99069;NSC-99069;STK402256;AKOS000263552;MS-8968;A4948;BB 0262416;CS-0152965;M1295;EN300-11132;EN300-832915;2-Methylcinnamic acid, predominantly trans, 99%;ETHYL4-(TERT-BUTOXYCARBONYLAMINO)BENZOATE;A845157;AI-942/25034752;Q-101986;F2121-0050;Z2417574586

Suppliers and Price of 2-Methylcinnamic Acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-Methylcinnamic Acid Edit

Chemical Property:

Melting Point:174 °C
Boiling Point:293.5°Cat760mmHg
Flash Point:199.3°C
PSA：37.30000
Density:1.147g/cm³
LogP:2.09280
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:162.068079557
Heavy Atom Count:12
Complexity:184

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1C=CC(=O)O
Isomeric SMILES:CC1=CC=CC=C1/C=C/C(=O)O

Technology Process of 2-Methylcinnamic Acid

There total 37 articles about 2-Methylcinnamic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 615-37-2
ortho-methylphenyl iodide

: 79-10-7
acrylic acid

: 939-57-1,2373-76-4,41397-71-1
(E)-3-(2-methylphenyl)acrylic acid

Guidance literature:: With potassium hydroxide; PS-PEG-NH-C(O)C6H4PPh2-PdCl(η³-C3H5); at 50 ℃;
DOI:10.1055/s-2002-35605

Reference yield: 91.0%

: 201230-82-2
carbon monoxide

: 889869-30-1
trans-1-(2-bromovinyl)-2-methylbenzene

: 939-57-1,2373-76-4,41397-71-1
(E)-3-(2-methylphenyl)acrylic acid

Guidance literature:: With [bmim]PF₆; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In water; at 100 ℃; for 20h; under 15001.2 Torr;
DOI:10.1021/jo052651p

Reference yield: 90.0%

: 64-18-6
formic acid

: C₉H₉I

: 939-57-1,2373-76-4,41397-71-1
(E)-3-(2-methylphenyl)acrylic acid

Guidance literature:: With palladium diacetate; triethylamine; dicyclohexyl-carbodiimide; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In N,N-dimethyl-formamide; at 100 ℃; for 20h; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.joc.7b01808