4-Chloro-1-(chloromethyl)-2-methoxybenzene

Base Information Edit

Chemical Name:4-Chloro-1-(chloromethyl)-2-methoxybenzene
CAS No.:101079-84-9
Molecular Formula:C₈H₈Cl₂O
Molecular Weight:191.057
Hs Code.:
DSSTox Substance ID:DTXSID201267158
Mol file:101079-84-9.mol

Synonyms:4-chloro-1-(chloromethyl)-2-methoxybenzene;101079-84-9;4-chloro-2-methoxybenzyl chloride;Anisole, 5-chloro-2-(chloromethyl)-;4-chloro-2-methoxy benzyl chloride;SCHEMBL2152147;DZNWZPDQZJANKH-UHFFFAOYSA-N;DTXSID201267158;BEA07984;AKOS010993954;FT-0747704;EN300-1968311

Suppliers and Price of 4-Chloro-1-(chloromethyl)-2-methoxybenzene

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Chloro-1-(chloromethyl)-2-methoxybenzene Edit

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:189.9952203
Heavy Atom Count:11
Complexity:119

Purity/Quality:

Safty Information:

Pictogram(s):
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MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)Cl)CCl

Technology Process of 4-Chloro-1-(chloromethyl)-2-methoxybenzene

There total 3 articles about 4-Chloro-1-(chloromethyl)-2-methoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 57479-70-6
2-methoxy-4-chlorobenzoic acid

: 101079-84-9
4-chloro-1-(chloromethyl)-2-methoxybenzene

Guidance literature:: With pyridine; thionyl chloride; borane; In tetrahydrofuran; diethyl ether;

Reference yield: 82.42%

: 90296-27-8
(4-chloro-2-methoxy-phenyl)methanol

: 101079-84-9
4-chloro-1-(chloromethyl)-2-methoxybenzene

Guidance literature:: With thionyl chloride; In dichloromethane; at 20 - 25 ℃; for 0.5h; Inert atmosphere; Reflux;

Reference yield:

: 78955-90-5
methyl 4-chloro-2-methoxybenzoate

: 101079-84-9
4-chloro-1-(chloromethyl)-2-methoxybenzene

Guidance literature:: Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere

2: thionyl chloride / dichloromethane / 6 h / 20 °C / Inert atmosphere

With lithium aluminium tetrahydride; thionyl chloride; In tetrahydrofuran; dichloromethane;