1,1-Dimethylguanidine sulfate

Base Information

• Chemical Name: 1,1-Dimethylguanidine sulfate
• CAS No.: 598-65-2
• Molecular Formula: C6H20N6O4S
• Molecular Weight: 272.329
• Hs Code.: 29252900
• NSC Number: 3715
• DSSTox Substance ID: DTXSID40922732
• Mol file: 598-65-2.mol

Synonyms:1,1-Dimethylguanidine sulfate;1186-46-5;311-77-3;1,1-dimethylguanidine;sulfuric acid;N,N-dimethylguanidine;N,N-dimethylguanidine sulphate;1,1-DIMETHYLGUANIDINESULFATE;NSC3715;Dimethylguanidinsulfat;SCHEMBL724776;1,1-dimethylguanidine sulphate;DTXSID40922732;NSC-3715;AKOS015950538;N,N-DIMETHYLGUANIDINE DISULFATE;Guanidine,N-dimethyl-, sulfate (2:1);Guanidine,1-dimethyl-, sulfate (2:1);AS-16141;FT-0745389;Sulfuric acid--N,N-dimethylguanidine (1/1);EN300-181449;1,1-Dimethylguanidine sulfate(1 pound masculine1)

Chemical Property of 1,1-Dimethylguanidine sulfate

Chemical Property:

• Appearance/Colour: white to off-white powder
• Vapor Pressure: 30.4mmHg at 25°C
• Melting Point: 300 °C (dec.)(lit.)
• Boiling Point: 104.7 °C at 760 mmHg
• Flash Point: 17.1 °C
• PSA: 136.09000
• LogP: 0.66950
• Storage Temp.: Inert atmosphere,Room Temperature
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 185.04702701
• Heavy Atom Count: 11
• Complexity: 138

Purity/Quality:

99% ^*data from raw suppliers

N,N-Dimethylguanidine sulfate 98+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CN(C)C(=N)N.OS(=O)(=O)O
• Uses: 1,1-Dimethylguanidine sulfate salt has been employed:as peroxide activator for bleaching cellulosic textilesin the synthesis of N2,N2-dimethyl-4-(1-methyl-1H-indol-3-yl)pyrimidine-2,5-diamine, substrate for the modified Pictet-Spengler reaction

Technology Process of 1,1-Dimethylguanidine sulfate

There total 1 articles about 1,1-Dimethylguanidine sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methylisothiourea sulphate (14527-26-5,867-44-7,147895-43-0) + dimethyl amine (124-40-3) → N,N-dimethylguanidine sulfate (598-65-2,1186-46-5)

Guidance literature:

With water;

Reference yield: 93.0%

2-(3-N,N-dimethylamino-prop-2-en-1-onyl)phenyldiphenylphosphine (877129-18-5) + N,N-dimethylguanidine sulfate (598-65-2,1186-46-5) → C6H4P(C6H5)2C4N2H2N(CH3)2 (1350639-41-6)

Guidance literature:

With potassium hydroxide; In ethanol; for 20h; Inert atmosphere; Reflux;

DOI:10.1002/ejic.201100659

Reference yield: 88.0%

N,N-dimethylguanidine sulfate (598-65-2,1186-46-5) + ethyl 4-(2,6-difluorophenyl)-3-oxobutanoate (221121-46-6) → 6-(2,6-difluorophenylmethyl)-3,4-dihydro-2-N,N-dimethylaminopyrimidin-4-(3H)-one

Guidance literature:

N,N-dimethylguanidine sulfate; ethyl 4-(2,6-difluorophenyl)-3-oxobutanoate; With ethanol; sodium; for 8h; Heating / reflux;

With water; acetic acid; pH=5;

upstream raw materials:

2-methylisothiourea sulphate

dimethyl amine

Downstream raw materials:

1,1-Dimethyl-semicarbazid

2‐dimethylamino‐5,6‐dimethyl‐4‐hydroxypyrimidine

Dimethyl-(4-phenyl-6-trifluoromethyl-pyrimidin-2-yl)-amine

[4-(4-Fluoro-phenyl)-6-isopropyl-pyrimidin-2-yl]-dimethyl-amine