1,1-Dimethylsemicarbazide

Base Information

• Chemical Name: 1,1-Dimethylsemicarbazide
• CAS No.: 22718-49-6
• Molecular Formula: C₃H₉N₃O
• Molecular Weight: 103.124
• Mol file: 22718-49-6.mol

Synonyms:1,1-dimethylsemicarbazide;22718-49-6;dimethylaminourea;Hydrazinecarboxamide, 2,2-dimethyl-;2,2-Dimethylhydrazinecarboxamide;dimethylsemi carbazide;SCHEMBL2034380;2,2-Dimethylhydrazine-1-carboxamide;MFCD19203658;AKOS006340277;CS-0450115;D3854;D90233

Chemical Property of 1,1-Dimethylsemicarbazide

Chemical Property:

• Melting Point: 138.0 to 142.0 °C
• PKA: 11.82±0.50(Predicted)
• PSA: 58.36000
• Density: 1.086g/cm³
• LogP: 0.22250
• XLogP3: -0.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 103.074561919
• Heavy Atom Count: 7
• Complexity: 70.6

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,1-Dimethylsemicarbazide >96.0%(GC)(T) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CN(C)NC(=O)N

Technology Process of 1,1-Dimethylsemicarbazide

There total 8 articles about 1,1-Dimethylsemicarbazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

trimethylsilyl isocyanate (1118-02-1) + N,N-Dimethylhydrazine (57-14-7) → 1,1-Dimethyl-semicarbazid (22718-49-6)

Guidance literature:

In hexane; at 60 ℃; for 1h;

DOI:10.1007/s11176-006-0016-0

Reference yield: 61.0%

N,N-Dimethylhydrazine (57-14-7) + (chloromethyl)isocyanatodimethylsilane (86845-05-8) → 1,1-Dimethyl-semicarbazid (22718-49-6)

Guidance literature:

In hexane; at 60 ℃; for 1h;

DOI:10.1007/s11176-006-0016-0

Reference yield:

N,N-dimethylguanidine sulfate (598-65-2,1186-46-5) → 1,1-Dimethyl-semicarbazid (22718-49-6)

Guidance literature:

With sodium hydroxide; sodium hypochlorite;

upstream raw materials:

potassium cyanate

N,N-Dimethylhydrazine

N,N-dimethylguanidine sulfate

2-hydroxyphenyl carbamate

Downstream raw materials:

1-benzoyl-2,2-dimethylhydrazine

Refernces

• 1、 Kirilin,Belova,Knyazev,Lega,Petrov,Chernyshev. "Organosilyl isocyanates. Reactions with hydrazine, 1,1-dimethylhydrazine, and 1-methyl-1-[2-(1-methylhydrazino)ethyl]hydrazine and structural and electronic characteristics". . p. 1930 - 1934. Retrieved 2008/02/03.