(1aS,1bR,2aS,6bR)-1a,1b,2a,6b-Tetrahydronaphtho[1,2-b:3,4-b']bisoxirene

Base Information

• Chemical Name: (1aS,1bR,2aS,6bR)-1a,1b,2a,6b-Tetrahydronaphtho[1,2-b:3,4-b']bisoxirene
• CAS No.: 58692-14-1
• Molecular Formula: C10H8O2
• Molecular Weight: 160.172
• Mol file: 58692-14-1.mol

Synonyms:(1aS,1bR,2aS,6bR)-1a,1b,2a,6b-Tetrahydronaphtho[1,2-b:3,4-b']bisoxirene

Chemical Property of (1aS,1bR,2aS,6bR)-1a,1b,2a,6b-Tetrahydronaphtho[1,2-b:3,4-b']bisoxirene

Chemical Property:

• PSA: 25.06000
• LogP: 1.58000

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (1aS,1bR,2aS,6bR)-1a,1b,2a,6b-Tetrahydronaphtho[1,2-b:3,4-b']bisoxirene

There total 6 articles about (1aS,1bR,2aS,6bR)-1a,1b,2a,6b-Tetrahydronaphtho[1,2-b:3,4-b']bisoxirene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

naphthalene (91-20-3,71998-51-1,72931-45-4) → Naphthalin-dioxid (58692-14-1,58717-74-1,80582-77-0,80582-78-1,80582-79-2)

Guidance literature:

With oxygen; isobutyraldehyde; cobalt(II) porphyrin; In acetonitrile; for 3h; Ambient temperature;

DOI:10.1016/0040-4039(96)00678-8

Reference yield:

naphthalene (91-20-3,71998-51-1,72931-45-4) → syn-1,2:3,4-naphthalene dioxide (58692-14-1) + α-naphthol (90-15-3) + rac-anti-naphthalene 1,2:3,4-dioxide (58717-74-1) + [1,4]naphthoquinone (130-15-4)

Guidance literature:

With ammonium acetate; dihydrogen peroxide; Mn(TPFPP)Cl; In acetonitrile; at 20 ℃; for 6h; Further Variations:; Catalysts; Product distribution;

DOI:10.1039/b313683c

Reference yield:

Trifluoro-acetic acid (1R,2S,3R,4S)-1,4-dibromo-3-(2,2,2-trifluoro-acetoxy)-1,2,3,4-tetrahydro-naphthalen-2-yl ester (83731-57-1) → syn-1,2:3,4-naphthalene dioxide (58692-14-1)

Guidance literature:

With sodium methylate; In tetrahydrofuran; at 0 ℃; for 3h; Yield given;

DOI:10.1021/jo00148a021

upstream raw materials:

naphthalene

cis-1,2,3,4-Tetrahydro-2,3-bis(trifluoroacetoxy)naphthalin

Trifluoro-acetic acid (1R,2S,3R,4S)-1,4-dibromo-3-(2,2,2-trifluoro-acetoxy)-1,2,3,4-tetrahydro-naphthalen-2-yl ester

Downstream raw materials:

naphthalene-1,4-dicarbonitrile

2,3-naphthalenediol

1,4-dimethoxynaphthalene

1,4-diphenoxynaphthalene

Refernces

• 1、 Mandal,Khanna,Iqbal. "Cobalt(II) porphyrin: A versatile catalyst for the oxidation of organic substrates with dioxygen and 2-methyl propanal". . p. 3769 - 3772. Retrieved 2007/10/03.
• 2、 Tsang, Wing-Sum,Griffin, Gary W.,Horning, M. G.,Stillwell, W. G.. "Chemistry of anti- and syn-1,2:3,4-Naphthalene Dioxides and Their Potential Relevance as Metabolic Intermediates". . p. 5339 - 5353. Retrieved 2007/10/02.